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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Effects of Prone Positioning on Transpulmonary Pressures and End-expiratory Volumes in Patients without Lung Disease

Authors: Abirami Kumaresan, M.D. et al Anesthesiology Newly Published on March 8, 2018. Background: The effects of prone positioning on esophageal pressures have not been investigated in mechanically ventilated patients. Our objective was to characterize effects of prone positioning on esophageal pressures, transpulmonary pressure, and lung volume, thereby assessing the potential utility of esophageal pressure measurements in […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Opioids No Better Than Nonopioids for Easing Common Types of Chronic Pain

Author: Lorenzo Di Francesco, MD, FACP, FHM Opioids are not better than nonopioid drugs for relieving back pain or pain related to hip or knee osteoarthritis, a JAMA study finds. Nearly 250 patients with moderate-to-severe chronic back pain or hip or knee osteoarthritis pain were randomized to receive either opioids or nonopioids. In the opioid group, patients […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Hyperinsulinemic Normoglycemia during Cardiac Surgery Reduces a Composite of 30-day Mortality and Serious In-hospital Complications: A Randomized Clinical Trial

Authors: Andra E. Duncan, M.D. et al Anesthesiology published on March 2018 Background: Hyperinsulinemic normoglycemia augments myocardial glucose uptake and utilization. We tested the hypothesis that hyperinsulinemic normoglycemia reduces 30-day mortality and morbidity after cardiac surgery. Methods: This dual-center, parallel-group, superiority trial randomized cardiac surgical patients between August 2007 and March 2015 at the Cleveland Clinic, Cleveland, Ohio, […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Dopamine D2-receptor Antagonist Droperidol Deepens Sevoflurane Anesthesia

Authors: Ryuhei Araki, M.D. et al Anesthesiology 4 2018, Vol.128, 754-763. Background: Although midbrain dopaminergic pathways are known to contribute to arousal and emergence from anesthesia, few reports exist regarding the anesthetic effects of dopamine D2 receptor antagonism in humans. This study examined the effect of the D2 receptor antagonist droperidol on sevoflurane anesthesia by examining α […]

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Uncategorized Published - 5 April, 2018    By - Dr Clemens
Effect of Epidural Infusion Bolus Delivery Rate on the Duration of Labor Analgesia: A Randomized Clinical Trial

Authors: Elizabeth M. S. Lange, M.D. et al     Author Notes Anesthesiology 4 2018, Vol.128, 745-753. Background: Programmed intermittent boluses of local anesthetic have been shown to be superior to continuous infusions for maintenance of labor analgesia. High-rate epidural boluses increase delivery pressure at the catheter orifice and may improve drug distribution in the epidural space. We hypothesized […]

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