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Uncategorized Published - 9 July, 2018    By - Dr Clemens
Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram

Authors: Annalotta Scheinin, M.D. et al     Anesthesiology 7 2018, Vol.129, 22-36. Background: Differentiating drug-related changes and state-related changes on the electroencephalogram during anesthetic-induced unconsciousness has remained a challenge. To distinguish these, we designed a rigorous experimental protocol with two drugs known to have distinct molecular mechanisms of action. We hypothesized that drug- and state-related changes can be […]

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Uncategorized Published - 9 July, 2018    By - Dr Clemens
Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome

Authors: Raquel S. Santos, Ph.D. et al   Anesthesiology 6 2018, Vol.128, 1193-1206. Background: The authors hypothesized that low tidal volume (VT) would minimize ventilator-induced lung injury regardless of the degree of mechanical power. The authors investigated the impact of power, obtained by different combinations of VT and respiratory rate (RR), on ventilator-induced lung injury in experimental mild acute […]

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Uncategorized Published - 8 July, 2018    By - Dr Clemens
Transcutaneous Electrical Nerve Stimulation May Not Effectively Relieve Low Back Pain

Transcutaneous electrical nerve stimulation (TENS) may not provide relief from lower back pain, but may be associated with short-term improvement (<6 weeks) in functional disability, according to a literature review published in Regional Anesthesia and Pain Medicine. Investigators evaluated 12 randomized controlled trials examining patients with low back pain undergoing TENS (n=350), control therapy (n=269; eg, placebo, sham, […]

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Uncategorized Published - 6 July, 2018    By - Dr Clemens
Opioid Cessation May Be More Successful When Depression Is Treated

Opioid cessation in patients with non-cancer pain may be more successful when depression is treated to remission, according to a study published in the February 2018 issue of the British Journal of Psychiatry. The study found that patients with chronic prescription opioid use and depression who adhered to antidepressant medications were more likely to stop opioids. […]

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Uncategorized Published - 6 July, 2018    By - Dr Clemens
Transversus abdominis plane (tap) block in laparoscopic colorectal surgery improves postoperative pain management: a meta-analysis

Authors: Hain E et al Colorectal Disease (Jan 2018) AIM Transversus abdominis plane (TAP) block is a locoregional anesthesia technique of growing interest in abdominal surgery. However, its efficacy following laparoscopic colorectal surgery is still debated. This meta-analysis aimed to assess the efficacy of TAP-block after laparoscopic colorectal surgery. METHOD All comparative studies focusing on […]

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