AUTHORS: Firth, Paul MBChB, BA et al Anesthesia & Analgesia May 01, 2025. BACKGROUND: The health care systems in low-income countries have extremely limited capacity to treat surgical diseases. The perioperative mortality rate has been suggested as a key quality metric to guide the expansion of care, but there is little information on how to […]
Read MoreAUTHORS: Fisher, Clark MD, PhD et al Anesthesia & Analgesia 140(5):p 1016-1027, May 2025. BACKGROUND: Although high-opioid anesthesia was long the standard for cardiac surgery, some anesthesiologists now favor multimodal analgesia and low-opioid anesthetic techniques. The typical cardiac surgery opioid dose is unclear, and the degree to which patients, anesthesiologists, and institutions influence this opioid dose […]
Read MoreAUTHORS: Georgakis, Nikolas A. BS et al Anesthesia & Analgesia 140(5):p 1004-1011, May 2025. BACKGROUND: Neuromuscular blocking agents (NMBAs) play an integral role in modern anesthesia by facilitating endotracheal tube placement, assisting with mechanical ventilation, and creating optimal surgical conditions. However, NMBAs can have deleterious side effects. The purpose of this study was to retrospectively analyze […]
Read MoreAUTHORS: Goeddel, Lee A. MD, MPH et al Anesthesia & Analgesia April 17, 2025. BACKGROUND: Prior studies identified thresholds for mean arterial pressure (MAP <65 mm Hg) and central venous pressure (CVP >12 mm Hg) beyond which risk for cardiac surgery-associated acute kidney injury (AKI) increases. Optimal hemodynamic targets—that is, where active protection from AKI […]
Read MoreAUTHORS: Hodapp, Joseph W. MD et al Anesthesia & Analgesia April 25, 2025. BACKGROUND: Focused anesthesia education may be beneficial for resource-constrained settings where inadequate training along with lack of infrastructure, staff, and supplies can contribute to high anesthetic morbidity and mortality rates. Some medical outreach efforts have transitioned from short-term and service-focused “missions” to […]
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