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Naldemedine, a peripherally acting µ-opioid receptor antagonist, was found to be safe and effective for increasing bowel movement frequency and improving quality of life in patients with chronic non-cancer pain and opioid-induced constipation (OIC), in a randomized placebo-controlled phase 3 trial published in Pain. In addition, naldemedine was not found to affect opioid analgesia or to […]
Read MoreIt might not just be old age causing forgetfulness. A new study, published in the journal Anaesthesia, found associations with decreased cognitive function and time under general anesthesia or neuraxial blockade. This observational study followed nearly a thousand middle-aged patients at the Wisconsin Registry for Alzheimer’s Prevention, testing the memory and executive function of participants on […]
Read MoreThe quadratus lumborum and posterior transversus abdominis plane (TAP) blocks can be used interchangeably after laparoscopic gynecologic surgeries, a Japanese research team concluded. Although visual analog scale (VAS) pain scores were lower in patients who received the quadratus lumborum block at some time points, the demand for postoperative fentanyl and other analgesics was similar between […]
Read MoreFor hospitals that can effectively collaborate across service lines to redesign care processes, the perioperative surgical home (PSH) model of care can help lower costs, improve outcomes and enhance patient satisfaction for surgical cases. Persuading hospital administration to commit resources to support new initiatives, however, can prove difficult in today’s health care environment. At the […]
Read MoreThe Society for the Advancement of Blood Management has released a list of five practices clinicians should question as part of the Choosing Wisely campaign. Here are the recommendations: Delay elective surgery in patients who have correctable anemia until the anemia has been treated. To avoid iatrogenic anemia, don’t order blood tests unless they are […]
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