Authors: Nygaard, Niels-Peter Brøchner Ph.D. et al Anesthesiology 142(6):p 1114-1126, June 2025. Background: The objective was to investigate whether cryoneurolysis was superior to sham in reducing pain intensity in patients with chronic knee osteoarthritis. The hypothesis was that cryoneurolysis is an effective and safe therapy to reduce chronic pain in patients with knee osteoarthritis. Methods: The […]
Read MoreAUTHORS: Chang MD, PhD et al Anesthesia & Analgesia May 16, 2025. BACKGROUND: The mechanisms by which sevoflurane protects the brain from hypoxic-ischemic brain injury (HIBI) are unknown. Ferroptosis occurs during HIBI and is regulated by the nuclear factor erythroid 2-related factor 2 (Nrf2). This study investigated the roles of Nrf2-regulated ferroptosis in sevoflurane postconditioning […]
Read MoreAuthors: Hussain, Nasir M.D., M.Sc. et al Anesthesiology 142(6):p 1127-1137, June 2025. Background: Both perineural and intravenous dexamethasone have been proposed as effective adjuncts that prolong the duration of peripheral nerve blocks. The authors sought to explore whether combining systemic with perineural dexamethasone yields any additive or synergistic effect on the characteristics and analgesic effects of […]
Read MoreAuthor: Claire Wallace Becker’s ASC Review Physician burnout rates have dropped below 45% for the first time since before the COVID-19 pandemic, according to a May 1 report from the American Medical Association. The AMA’s Organizational Biopsy report surveyed 18,000 physicians across 43 states and more than 100 health systems. According to the most recent report, 43.2% […]
Read MoreAUTHORS: Talmy, Tomer MD, MBA et al Anesthesia & Analgesia May 16, 2025. BACKGROUND: Endotracheal intubation is essential for airway management in trauma patients but may cause hemodynamic instability and delay critical resuscitation measures. Recent studies have suggested that emergency department (ED) intubation may be linked with higher mortality compared to operating room (OR) intubation […]
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