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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome

Authors: Jacopo Fumagalli, M.D. et al Anesthesiology 5 2019, Vol.130, 791-803. What We Already Know about This Topic: Obesity increases the propensity to atelectasis in acute respiratory distress syndrome, but the optimal approach to reversing this atelectasis is uncertain What This Article Tells Us That Is New: A clinical crossover study comparing three approaches to titrate […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Can the Brain Predict Fluid Responsiveness?

Authors: Elliot Long, B.M.B.S., F.R.A.C.P. et al Anesthesiology 5 2019, Vol.130, 674-676. “Transfontanelle measurement of respiratory variation in internal carotid artery blood flow peak velocity is a novel method for predicting fluid responsiveness [in infants].” Image: TranscranialUS. Resuscitation with IV fluid is a ubiquitous first-line form of acute circulatory support in emergency medicine, critical care, […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Aquaporin 5 –1364A/C Promoter Polymorphism Is Associated with Pulmonary Inflammation and Survival in Acute Respiratory Distress Syndrome

Authors: Tim Rahmel, M.D. et al Anesthesiology 3 2019, Vol.130, 404-413. What We Already Know about This Topic: Acute respiratory distress syndrome is defined according to clinical criteria, but lack of precise characterization may contribute to negative trials and impede personalized care. Polymorphisms of aquaporin-5, a key mediator of inflammation, may impact outcome. What This Article […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
Nociception-guided versus Standard Care during Remifentanil–Propofol Anesthesia: A Randomized Controlled Trial

Authors: Fleur S. Meijer, M.D. et al Anesthesiology 5 2019, Vol.130, 745-755. What We Already Know about This Topic: The nociception level index (Medasense Biometrics Ltd., Ramat Gan, Israel), is a reliable measure of moderate to intense noxious stimulation during anesthesia and surgery What This Article Tells Us That Is New: In a randomized trial in […]

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Uncategorized Published - 23 April, 2019    By - Dr Clemens
US Cancer Patients Are Undergoing CRISPR Tests For The First Time

By David Grossman Popular Mechanics The high-profile experimental technique got a bad rap in 2018. Scientists are trying for a second introduction in 2019. For the first time, doctors in the United States have used cutting-edge CRISPR technology to treat cancer patients. Two cancer patients participating in a study with the University of Pennsylvania in […]

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