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Uncategorized Published - 24 June, 2019    By - Dr Clemens
Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery

Authors: Subramaniam B et al Journal of the American Medical Association (JAMA) 321 (7), 686-696 (Feb 2019) Importance Postoperative delirium is common following cardiac surgery and may be affected by choice of analgesic and sedative. Objective To evaluate the effect of postoperative intravenous (IV) acetaminophen (paracetamol) vs placebo combined with IV propofol vs dexmedetomidine on […]

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Uncategorized Published - 24 June, 2019    By - Dr Clemens
Aerobic Exercise and Cognitive Performance in Younger and Older Adults

I thought this was interesting so I wanted to share this with our readers. Authors: Stern Y et al. Neurology 2019 Jan 30 More evidence supports positive effects of aerobic exercise on cognitive outcomes, especially in older adults. Aerobic exercise can improve cognition and increase cortical thickness in older adults. In this randomized, community-based clinical trial, […]

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Uncategorized Published - 24 June, 2019    By - Dr Clemens
Excess Risk for Kidney Disease in Young Military Personnel Who Use NSAIDs

Authors: Nelson DA et al. JAMA Net Open 2019 Feb 15 Frequent use of nonsteroidal anti-inflammatory drugs was associated with ≈50 more kidney disease cases per 100,000 people annually. Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with kidney disease in older patients. In this retrospective cohort study, researchers explored the health effects of NSAIDs in 760,000 […]

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Uncategorized Published - 24 June, 2019    By - Dr Clemens
Persistent breast pain in post-surgery breast cancer survivors and women with no history of breast surgery or cancer: associations with pain catastrophizing, perceived breast cancer risk, breast cancer worry, and emotional distress

Authors: Bovbjerg D et al Acta Oncologica 1-6 (Feb 2019) BACKGROUND Persistent breast pain (PBP) is prevalent among breast cancer survivors and has powerful negative psychological consequences. The present study provided a first test of the hypothesis that: (a) pain catastrophizing, (b) heightened perceived risk of cancer, and (c) worry that pain indicates cancer may […]

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Uncategorized Published - 24 June, 2019    By - Dr Clemens
Intensity of Withdrawal Symptoms During Opioid Taper in Patients with Chronic Pain-Individualized or Fixed Starting Dosage?

Authors: Bienek N et al Pain Medicine (Feb 2019) OBJECTIVE Controlled opioid withdrawal is recommended for patients with chronic noncancer pain (CNCP) with insufficient pain reduction or intolerable side effects while on opioid treatment. Few studies have investigated the management of opioid withdrawal (OW). Most common are protocols with an individualized starting dosage (ISD), calculated […]

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