Author: MIKE STOBBE Prescriptions of the overdose-reversing drug naloxone are soaring, and experts say that could be a reason overdose deaths have stopped rising for the first time in nearly three decades. The number of naloxone prescriptions dispensed by U.S. retail pharmacies doubled from 2017 to last year, rising from 271,000 to 557,000, health officials […]
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Read MoreAUTHORS: Candiotti, Keith A. MD et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1098-1105 BACKGROUND: Postoperative nausea and vomiting (PONV) occurs commonly in surgical patients despite widespread prophylactic antiemetic use. Rescue options are currently limited. 5HT3 antagonists are most frequently used for prophylaxis, but if they fail, additional doses are […]
Read MoreAUTHORS: Holmgaard, Frederik BMSc et al Anesthesia & Analgesia: June 2019 – Volume 128 – Issue 6 – p 1081-1088 BACKGROUND: Near-infrared spectroscopy (NIRS) is used worldwide to monitor regional cerebral oxygenation (rScO2) during cardiopulmonary bypass (CPB). Intervention protocols meant to mitigate cerebral desaturation advocate to increase mean arterial pressure (MAP) when cerebral desaturation occurs. However, […]
Read MoreAuthors: Molero Y et al. BMJ 2019 Jun 12 Multiple adverse behavioral and psychomotor associations are found with these drugs although the effects might be confined to pregabalin. Clinicians often prescribe gabapentin and pregabalin for pain, sleep, and anxiety symptoms, and some view these drugs as safe alternatives to benzodiazepines and opioids in, for example, patients […]
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