Authors: Ferrari MD et al. Lancet 2019 Aug 16 Tessitore A and Russo A. Lancet 2019 Aug 16 Fremanezumab is a well-tolerated and effective preventive therapy in patients with migraine for whom two to four preventives have failed. Researchers conducted a phase IIIb randomized controlled trial with fremanezumab, a calcitonin gene-related peptide (CGRP) monoclonal antibody, funded by the […]
Read MoreAuthors: Frederik Vilhelmsen et al BMC Anesthesiology volume 19, Article number: 165 (2019) Background Nerve block of the lateral femoral cutaneous nerve (LFCN) is a predominantly sensory block. It reduces pain following total hip arthroplasty (THA), but the non-responder rate is high. We hypothesized, that an increased volume of ropivacaine, would result in greater coverage of incisions used for THA. […]
Read MoreMariana R. S. Ceschim, MD and Keith A. Candiotti, MD Anesthesiology News In contradiction to the advances in medicine in recent decades, infectious diseases are on the rise.1 Environmental changes due to population shifts, climate change and microbial adaptations have prompted the spread of emerging and reemerging infections.1,2 These diseases can present with airway complications, respiratory and […]
Read MoreAUTHORS: Naylor, Amanda J. MA et al Anesthesia & Analgesia: September 2019 BACKGROUND: Continuous blood pressure monitoring may facilitate early detection and prompt treatment of hypotension. We tested the hypothesis that area under the curve (AUC) mean arterial pressure (MAP) <65 mm Hg is reduced by continuous invasive arterial pressure monitoring. METHODS: Adults having noncardiac surgery were randomly […]
Read MoreAUTHORS: Sabourdin, Nada MD et al Anesthesia & Analgesia: September 2019 BACKGROUND: Pupillometry monitoring under general anesthesia is based on the assumption that pupillary diameter variations reflect the adequacy of the provided analgesia to the intensity of the nociceptive surgical stimulus. The accurate interpretation of pupillometric data requires establishing clearly what the expected baseline unstimulated pupillary diameter […]
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