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Uncategorized Published - 2 June, 2020    By - Dr Clemens
Staffing with disease-based epidemiologic indices may reduce shortage of intensive care unit staff during the COVID-19 pandemic

AUTHORS: Mascha, Edward J. PhD et al Anesthesia & Analgesia: April 2020 Purpose: Healthcare worker (HCW) safety is of pivotal importance during a pandemic such as Coronavirus Disease 2019 (COVID-19), and employee health and well-being ensures functionality of healthcare institutions. This is particularly true for an intensive care unit (ICU) where highly specialized staff cannot be readily […]

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Uncategorized Published - 2 June, 2020    By - Dr Clemens
Remdesivir Results Published

NEJM Journal Watch By Kelly Young Edited by Jaye Elizabeth Hefner, MD Preliminary results regarding the use of remdesivir against novel coronavirus disease (COVID-19) have been updated and published in the New England Journal of Medicine. (An earlier accounting, which we also reported here, led to the drug’s emergency approval by the FDA.) Over 1000 hospitalized patients […]

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Uncategorized Published - 1 June, 2020    By - Dr Clemens
Positive End-Expiratory Pressure During Anesthesia for Prevention of Postoperative Pulmonary Complications

AUTHORS: Zhang, Pengcheng MD et al Anesthesia & Analgesia: April 2020 – Volume 130 – Issue 4 – p 879-889 BACKGROUND:  Whether intraoperative positive end-expiratory pressure (PEEP) can reduce the risk of postoperative pulmonary complications remains controversial. We performed a systematic review of currently available literature to investigate whether intraoperative PEEP decreases pulmonary complications in […]

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Uncategorized Published - 1 June, 2020    By - Dr Clemens
Prophylactic Cefazolin Dosing in Women With Body Mass Index >35 kg·m−2 Undergoing Cesarean Delivery

AUTHORS: Eley, Victoria A. PhD et al Anesthesia & Analgesia: April 2020 BACKGROUND: Obesity is a risk factor for surgical site infection after cesarean delivery. There is inadequate pharmacokinetic data available regarding prophylactic cefazolin dosing in obese pregnant women. We aimed to describe the plasma and interstitial fluid (ISF) pharmacokinetics of cefazolin in obese women […]

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Uncategorized Published - 1 June, 2020    By - Dr Clemens
Incidence of Anaphylaxis to Sugammadex in a Single-Center Cohort of 19,821 Patients

AUTHORS: Burbridge, Mark A. MD Anesthesia & Analgesia: March 2020 BACKGROUND: Sugammadex is a modified cyclodextrin that is being increasingly used in anesthetic practice worldwide for the reversal of the aminosteroid neuromuscular blockers rocuronium and vecuronium. Its safety profile, however, is incompletely understood. One such aspect is the incidence of anaphylactic reactions that occur after […]

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