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Uncategorized Published - 7 October, 2020    By - Dr Clemens
Common antioxidant enzyme may provide potential treatment for COVID-19

By University of California, Los Angeles Simple diagram showing catalase kick starting reaction that converts hydrogen peroxide into water and oxygen. Credit: Yunfeng Lu research group/UCLA Researchers from UCLA and China have found that catalase, a naturally occurring enzyme, holds potential as a low-cost therapeutic drug to treat COVID-19 symptoms and suppress the replication of […]

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Uncategorized Published - 6 October, 2020    By - Dr Clemens
Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation

Authors: Eric S. Schwenk, M.D. et al  Anesthesiology October 2020, Vol. 133, 801–811. Background Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable earlier ambulation than bupivacaine. This study was designed to test the hypothesis […]

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Uncategorized Published - 6 October, 2020    By - Dr Clemens
Preoperative Frailty Predicts Postoperative Neurocognitive Disorders After Total Hip Joint Replacement Surgery

AUTHORS: Evered, Lis A. PhD et al Anesthesia & Analgesia: May 27, 2020 BACKGROUND: Frailty is a reduced capacity to recover from a physiologically stressful event. It is well established that preoperative frailty is associated with poor postoperative outcomes, but it is unclear if this includes cognitive decline following anesthesia and surgery. This retrospective observational […]

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Uncategorized Published - 6 October, 2020    By - Dr Clemens
End-tidal to Arterial Gradients and Alveolar Deadspace for Anesthetic Agents

Author: Philip J. Peyton, M.D., Ph.D., M.B.B.S., F.A.N.Z.C.A. et al  Anesthesiology September 2020, Vol. 133, 534–547. Background According to the “three-compartment” model of ventilation-perfusion () inequality, increased  scatter in the lung under general anesthesia is reflected in increased alveolar deadspace fraction (Vda/Va) customarily measured using end-tidal to arterial (a-a) partial pressure gradients for carbon dioxide. a-a gradients for […]

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Uncategorized Published - 6 October, 2020    By - Dr Clemens
Anesthesiology’s role in stroke care

Anesthesiology Today Annual Meeting Edition Anesthesiologists can play a critical role in assessing and reducing the risk of perioperative and acute ischemic stroke in non-cardiac surgery patients through careful screening, managing antithrombotic therapy, and even scheduling optimal timing for elective surgery. Those considerations as well as keeping the anesthesiologist safe during the pandemic were the […]

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