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Uncategorized Published - 11 November, 2020    By - Dr Clemens
New method could help increase effectiveness of vaccines against coronavirus

Reviewed by Emily Henderson, B.Sc. News Medical Life Science A University at Buffalo-led research team has discovered a technique that could help increase the effectiveness of vaccines against the novel coronavirus, the virus that causes COVID-19. Jonathan F. Lovell, PhD, associate professor in the Department of Biomedical Engineering at UB, is the primary investigator on […]

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Uncategorized Published - 10 November, 2020    By - Dr Clemens
Macintosh Videolaryngoscope for Intubation in the Operating Room

AUTHORS: De Jong, Audrey MD, PhD et al Anesthesia & Analgesia: July 2020 BACKGROUND: “Macintosh”-videolaryngoscopes (VLs) are VLs that allow both direct and indirect laryngoscopy for intubation. We describe the decision-making and implementation-processes that our hospital used regarding the choice of device. We compared the performances of 4 Macintosh-VLs both in direct and indirect laryngoscopy. […]

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Uncategorized Published - 10 November, 2020    By - Dr Clemens
Risk Factors for Intraoperative Hypoglycemia in Children

AUTHORS: Riegger, Lori Q. MD et al Anesthesia & Analgesia: June 2020 BACKGROUND: Intraoperative hypoglycemia can result in devastating neurologic injury if not promptly diagnosed and treated. Few studies have defined risk factors for intraoperative hypoglycemia. The authors sought to characterize children with intraoperative hypoglycemia and determine independent risk factors in a multicenter cohort. METHODS: […]

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Uncategorized Published - 10 November, 2020    By - Dr Clemens
Hypotension Prediction Index for Prevention of Hypotension during Moderate- to High-risk Noncardiac Surgery

Authors: Kamal Maheshwari, M.D., M.P.H. et al  Anesthesiology December 2020, Vol. 133, 1214–1222. Background The Hypotension Prediction Index is a commercially available algorithm, based on arterial waveform features, that predicts hypotension defined as mean arterial pressure less than 65 mmHg for at least 1 min. We therefore tested the primary hypothesis that index guidance reduces the […]

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Uncategorized Published - 10 November, 2020    By - Dr Clemens
Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via α-2 Adrenergic Receptor

AUTHORS: Sun, Mingyang MD, PhD et al Anesthesia & Analgesia: November 2020 BACKGROUND: Anesthetic sevoflurane induces tau phosphorylation and cognitive impairment in young mice. The underlying mechanism and the targeted interventions remain largely unexplored. We hypothesized that dexmedetomidine and clonidine attenuated sevoflurane-induced tau phosphorylation and cognitive impairment by acting on α-2 adrenergic receptor. METHODS: Six-day-old […]

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