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Uncategorized Published - 4 December, 2020    By - Dr Clemens
Effect of a stepwise opioid-sparing analgesic protocol on in-hospital oxycodone use and discharge prescription after cesarean delivery

DG Journal Club AUTHORS Ruth Landau, Erik Romanelli et al. Reg Anesth Pain Med. 2020 Nov 10 INTRODUCTION Opioid exposure during hospitalization for cesarean delivery increases the risk of new persistent opioid use. We studied the effectiveness of stepwise multimodal opioid-sparing analgesia in reducing oxycodone use during cesarean delivery hospitalization and prescriptions at discharge. METHODS […]

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Uncategorized Published - 4 December, 2020    By - Dr Clemens
Presence of Pneumocystis jirovecii in critically ill patients with COVID-19

DG Alerts An unexpectedly high proportion of Pneumocystis jirovecii-positive pulmonary samples was observed in critically ill coronavirus disease 2019 (COVID-19) patients, according to a study published in Journal of Infection. “Based on our findings, we advocate systematically searching for P. jirovecii in deep respiratory specimens in these patients. We believe that this strategy may be useful in limiting enhanced […]

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Uncategorized Published - 3 December, 2020    By - Dr Clemens
Intranasal oxytocin as a treatment for chronic pelvic pain

This is for our readers who treat pain patients AUTHORS: Michelle J Flynn, Tavis S Campbell et al. Int J Gynaecol Obstet. 2020 Oct 28 OBJECTIVES To investigate the effect of intranasal oxytocin on chronic pelvic pain in a randomized, double-blind, within-subject crossover trial. Aims included: (1) determine intranasal oxytocin’s effect on pain intensity and […]

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Uncategorized Published - 3 December, 2020    By - Dr Clemens
TRPV1-Targeted Drugs in Development for Human Pain Conditions

DG Journal Club AUTHORS Mircea Iftinca, Manon Defaye et al. Drugs. 2020 Nov 9 The transient receptor potential vanilloid-1 (TRPV1) is a non-specific cation channel known for its sensitivity to pungent vanilloid compound (i.e. capsaicin) and noxious stimuli, including heat, low pH or inflammatory mediators. TRPV1 is found in the somatosensory system, particularly primary afferent […]

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Uncategorized Published - 3 December, 2020    By - Dr Clemens
93% of patients with type 2 diabetes are at an increased risk of a fatal heart attack or stroke

Author: Michael Walter Cardiovascular Business News A whopping 93% of adult patients with type 2 diabetes (T2D) are at a high risk of experiencing a fatal acute myocardial infarction (AMI) or stroke, according to new research published in the European Journal of Preventive Cardiology. The study was focused on data out of Catalonia, Spain, but its findings […]

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