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Uncategorized Published - 29 January, 2021    By - Dr Clemens
Intermediate-dose anticoagulation, aspirin tied to lower incidence of in-hospital death among inpatients with COVID-19

DG Alerts Intermediate-dose anticoagulation and aspirin were each associated with a lower cumulative incidence of in-hospital death among hospitalised patients with coronavirus disease 2019 (COVID-19), according to a study published in the American Journal of Hematology. “High VTE (venous thromboembolism) rates have been reported in critically ill patients with COVID-19 despite the use of prophylactic anticoagulation,” […]

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Uncategorized Published - 28 January, 2021    By - Dr Clemens
Patient and Procedural Determinants of Postoperative Pain Trajectories

Authors: Terrie Vasilopoulos, Ph.D. et al  Anesthesiology January 2021. Background The primary goal of this study was to evaluate patterns in acute postoperative pain in a mixed surgical patient cohort with the hypothesis that there would be heterogeneity in these patterns. Methods This study included 360 patients from a mixed surgical cohort whose pain was […]

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Uncategorized Published - 28 January, 2021    By - Dr Clemens
Fast-spiking Interneurons Contribute to Propofol-induced Facilitation of Firing Synchrony in Pyramidal Neurons of the Rat Insular Cortex

Authors: Yuko Koyanagi, D.D.S., Ph.D. et al  Anesthesiology February 2021, Vol. 134, 219–233. Background The general anesthetic propofol induces frontal alpha rhythm in the cerebral cortex at a dose sufficient to induce loss of consciousness. The authors hypothesized that propofol-induced facilitation of unitary inhibitory postsynaptic currents would result in firing synchrony among postsynaptic pyramidal neurons that […]

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Uncategorized Published - 28 January, 2021    By - Dr Clemens
The Prevalence of Back and Leg Pain and the Cross-sectional Association With Adverse Health Outcomes in Community Dwelling Older Adults in England

DG Journal Club AUTHORS: Esther Williamson, Maria T Sanchez Santos et al. Spine (Phila Pa 1976). 2021 Jan 1; 46(1): 54-61 STUDY DESIGN Cross-sectional analysis of the Oxford Pain, Activity and Lifestyle (OPAL) Cohort Study. OBJECTIVE The aim of this study was to assess the prevalence of back pain (BP) and leg pain and determine […]

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Uncategorized Published - 28 January, 2021    By - Dr Clemens
Pregnant women unlikely to pass SARS-CoV-2 infection to newborns

DG Alerts A study published in JAMA Network Open shows that there was no maternal viremia, placental infection, or vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a cohort of pregnant women with coronavirus disease 2019 (COVID-19). In addition, compromised transplacental transfer of anti–SARS-CoV-2 antibodies with robust transfer of influenza-specific immunity and nonoverlapping placental […]

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