Pharmacy Times Officials with the FDA have approved bupivacaine solution (Posimir; DURECT Corporation) for infiltration use in adults. The drug is a novel, nonopioid, sustained-release local analgesic indicated for use as postsurgical analgesia for up to 72 hours following arthroscopic subacromial decompression. It is administered into the subacromial space under direct arthroscopic visualization. “The first 72 […]
Read MoreAUTHORS: Nasr, Viviane G. MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1607-1615 BACKGROUND: Utilizing the intrinsic surgical risk (ISR) and the patient’s chronic and acute conditions, this study aims to develop and validate a comprehensive predictive model of perioperative morbidity in children undergoing noncardiac surgery. METHODS: […]
Read MoreAUTHORS: Yuan, Yuchen MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1573-1581 BACKGROUND: It remains unclear whether the benefits of performing perioperative allogeneic red blood cell (RBC) transfusion outweigh the risks of postoperative wound infection. The aim of this study was to assess the impact of perioperative RBC […]
Read MoreAUTHORS: Yu, Wantong MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1599-1606 BACKGROUND: Oxycodone has been shown to be an effective analgesic for early postoperative analgesia, especially for abdominal operations associated with severe visceral pain. However, the dose needed varies depending on the operation and application of […]
Read MoreAUTHORS: Kim, Jong Hae MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1589-1598 BACKGROUND: Intraoperative monitoring with pupillometry has shown promising results for nociception/antinociception balance monitoring. However, its benefits in clinical practice remain unproven. The aim of this study was to evaluate the efficacy of intraoperative pupillometry […]
Read More