AUTHORS: Lee, Ji-Hyun MD, PhD et al Anesthesia & Analgesia: November 2020 BACKGROUND: General anesthesia-induced atelectasis is common, and persistent postoperative atelectasis is associated with pulmonary complications. We aimed to evaluate the preventive effects of a high-flow nasal cannula (HFNC) on postoperative atelectasis and respiratory complications in infants and small children. METHODS: In this prospective […]
Read MoreAUTHORS: Kain, Alexandra S. BA et al Anesthesia & Analgesia: November 2020 BACKGROUND: This investigation aimed to examine the impact of parental psychosocial variables on the administration of opioids to young children experiencing postoperative pain. METHODS: Participants in this longitudinal analysis were children ages 2–12 undergoing tonsillectomy with or without adenoidectomy and their parents. Parents […]
Read MoreAUTHORS: Lohela, Terhi J. MD, PhD et al Anesthesia & Analgesia: November 2020 BACKGROUND: Several opioids are metabolized by the inducible cytochrome P450 (CYP) 3A isozymes. Coadministration with strong inducers of drug metabolism, such as rifampin, can dramatically reduce systemic exposure to these opioids. As the CYP metabolism of hydromorphone is of minor importance, we […]
Read MoreAUTHORS: Gregory, Anne MD, MSc, FRCPC et al Anesthesia & Analgesia: November 2020 BACKGROUND: Intraoperative hypotension (IOH) occurs frequently during surgery and may be associated with organ ischemia; however, few multicenter studies report data regarding its associations with adverse postoperative outcomes across varying hemodynamic thresholds. Additionally, no study has evaluated the association between IOH exposure […]
Read MoreAUTHORS: Mittel, Aaron M. MD et al Anesthesia & Analgesia: October 2020 Background: Covid-19 emerged as a public health crisis that disrupted normal patterns of health care in the New York City metropolitan area. In preparation for a large influx of critically ill patients, operating rooms (ORs) at NewYork-Presbyterian Hospital/Columbia University Irving Medical Center (NYP-Columbia) […]
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