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Uncategorized Published - 10 March, 2021    By - Dr Clemens
Anesthesia for children with complete trisomy 18 (Edwards syndrome)

DG Journal Club Erin E Birmingham, Astrid G Stucke et al. Paediatr Anaesth. 2021 Feb 28 BACKGROUND Trisomy 18 or Edwards syndrome is the second most common aneuploidy with a prevalence between 1/3000 and 1/10 000 live births. The syndrome encompasses malformations of the central nervous, cardiac, respiratory, gastrointestinal, and genitourinary systems. Trisomy 18 carries a […]

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Uncategorized Published - 10 March, 2021    By - Dr Clemens
Balanced Opioid-free Anesthesia with Dexmedetomidine versus Balanced Anesthesia with Remifentanil for Major or Intermediate Noncardiac Surgery

Authors: Helene Beloeil, M.D., Ph.D. et al Anesthesiology April 2021, Vol. 134, 541–551. Background It is speculated that opioid-free anesthesia may provide adequate pain control while reducing postoperative opioid consumption. However, there is currently no evidence to support the speculation. The authors hypothesized that opioid-free balanced anesthetic with dexmedetomidine reduces postoperative opioid-related adverse events compared with […]

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Uncategorized Published - 10 March, 2021    By - Dr Clemens
Case 2020–11: “I Can’t Take It Anymore”

ASA Monitor Vol 84 Issue 11 Case presentation:A trauma patient from the emergency department showed up as a “surprise” to the OR with no known history. The patient was shot multiple times in the head, chest, and abdomen. The surgeon told us that the patient arrested in the trauma bay and a thoracotomy was done […]

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Uncategorized Published - 10 March, 2021    By - Dr Clemens
Complications as a Mediator of the Perioperative Frailty–Mortality Association

Authors: Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C. et al Anesthesiology April 2021, Vol. 134, 577–587. Background Preoperative frailty is strongly associated with postoperative complications and mortality. However, the pathways between frailty, postoperative complications, and mortality are poorly described. The authors hypothesized that the occurrence of postoperative complications would mediate a substantial proportion of the total effect […]

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Uncategorized Published - 10 March, 2021    By - Dr Clemens
Dysnatremia a predictor for morbidity and mortality in hospitalised patients with COVID-19

DG Alerts Abnormal sodium levels during hospitalisation was a risk factor for poor prognosis, with hypernatremia and hyponatremia being associated with a greater risk of death and respiratory failure, respectively, in patients with coronavirus disease 2019 (COVID-19), according to a study published in The Journal of Clinical Endocrinology & Metabolism. “Hypernatremia at any timepoint during hospital […]

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