Authors: Ryan M. Hijazi, D.O. et al Anesthesiology April 2021, Vol. 134, 552–561. Background Recent work suggests that having aortic valve surgery in the morning increases risk for cardiac-related complications. This study therefore explored whether mortality and cardiac complications, specifically low cardiac output syndrome, differ for morning and afternoon cardiac surgeries. Methods The study included adults […]
Read MoreAuthors: Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H. et al Anesthesiology April 2021, Vol. 134, 562–576. Background Protective ventilation may improve outcomes after major surgery. However, in the context of one-lung ventilation, such a strategy is incompletely defined. The authors hypothesized that a putative one-lung protective ventilation regimen would be independently associated with decreased odds of pulmonary […]
Read MoreAuthor: Aislinn Antrim Pharmacy Times Adverse effects, such as strange dreams, insomnia, and sleep disorders may be more likely for patients with a history of cardiovascular health issues. Although depression may occur during treatment with beta blockers, new research suggests that the drugs are not the likely cause. Beta-blockers are used to reduce heart rate, […]
Read MoreNEJM Journal Watch By Kelly Young Edited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD Osteopathic manipulative treatment had a statistically significant but small effect on low back pain in a randomized trial in JAMA Internal Medicine. The researchers question the clinical usefulness of the treatment. Some 400 people in France with nonspecific subacute or […]
Read MoreThe Postoperative and Opioid-free Anesthesia (POFA) Randomized Clinical Trial Authors: Helene Beloeil, M.D., Ph.D. et al Anesthesiology April 2021, Vol. 134, 541–551. Background It is speculated that opioid-free anesthesia may provide adequate pain control while reducing postoperative opioid consumption. However, there is currently no evidence to support the speculation. The authors hypothesized that opioid-free balanced anesthetic […]
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