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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Do Elderly Patients With Diastolic Dysfunction Require Higher Doses of Norepinephrine During General Anesthesia for Noncardiac Surgeries?

AUTHORS: Kahl, Ursula MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 420-429 BACKGROUND:  Diastolic dysfunction is a risk factor for postoperative major cardiovascular events. During anesthesia, patients with diastolic dysfunction might experience impaired hemodynamic function and worsening of diastolic function, which in turn, might be associated with […]

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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Nonopioid GTS-21 Mitigates Burn Injury Pain in Rats by Decreasing Spinal Cord Inflammatory Responses

AUTHORS: Zhou, Yinhui MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 240-252 Background:  Burn injury (BI) pain consists of inflammatory and neuropathic components and activates microglia. Nicotinic alpha 7 acetylcholine receptors (α7AChRs) expressed in microglia exhibit immunomodulatory activity during agonist stimulation. Efficacy of selective α7AChR agonist GTS-21 […]

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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Postoperative Morbidity and Mortality in Diabetic Patients After Fast-Track Hip and Knee Arthroplasty

AUTHORS: Ortved, Milla MD et al Anesthesia & Analgesia: November 20, 2020 – Volume – Issue – 10. BACKGROUND:  Diabetes increases the risk of adverse outcomes in surgical procedures, including total hip and knee arthroplasty (THA/TKA), and the prevalence of diabetic patients undergoing these procedures is high, ranging from approximately 8% to 20%. However, there […]

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Uncategorized Published - 30 March, 2021    By - Dr Clemens
Real-Time Injection Pressure Sensing and Minimal Intensity Stimulation Combination During Ultrasound-Guided Peripheral Nerve Blocks

AUTHORS: Varobieff, Maxime MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 556-565 BACKGROUND:  Nerve damage can occur after peripheral nerve block (PNB). Ultrasound guidance does not eliminate the risk of intraneural injection or nerve injury. Combining nerve stimulation and injection pressure (IP) monitoring with ultrasound guidance has […]

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Uncategorized Published - 29 March, 2021    By - Dr Clemens
Efficiency Metrics at an Academic Freestanding Ambulatory Surgery Center: Analysis of the Impact on Scheduled End-Times

AUTHORS: Reeves, J. Jeffery MD et al Anesthesia & Analgesia: November 18, 2020 – Volume – Issue – 10. BACKGROUND:  Understanding the impact of key metrics on operating room (OR) efficiency is important to optimize utilization and reduce costs, particularly in freestanding ambulatory surgery centers. The aim of this study was to assess the association […]

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