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Uncategorized Published - 15 April, 2021    By - Dr Clemens
Pain Catastrophizing Mediates and Moderates the Link Between Acute Pain and Working Memory

DG Journal Club AUTHORS: Philip M Procento, Kevin L Rand et al. J Pain. 2021 Mar 13 The bidirectional relationship between pain and working memory (WM) deficits is well-documented but poorly understood. Pain catastrophizing – exaggerated, negative cognitive and emotional responses toward pain – may contribute to WM deficits by occupying finite, shared cognitive resources. […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

AUTHORS: Ing, Caleb MD, MS et al Anesthesia & Analgesia: January 22, 2021 – Volume – Issue – 10 BACKGROUND: Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
A Novel Perioperative Multidose Methadone-Based Multimodal Analgesic Strategy in Children Achieved Safe and Low Analgesic Blood Methadone Levels Enabling Opioid-Sparing Sustained Analgesia With Minimal Adverse Effects

AUTHORS: Sadhasivam, Senthilkumar MD, MPH, MBA, FASA et al Anesthesia & Analgesia: January 21, 2021 – Volume – Issue – 10. BACKGROUND: Intraoperative methadone, a long-acting opioid, is increasingly used for postoperative analgesia, although the optimal methadone dosing strategy in children is still unknown. The use of a single large dose of intraoperative methadone is controversial […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
The Bitter and the Sweet: Relationship of Lactate, Glucose, and Mortality After Severe Blunt Trauma

AUTHORS: Richards, Justin E. MD et al Anesthesia & Analgesia: December 30, 2020 – Volume – Issue – 10. BACKGROUND: Hyperglycemia is associated with mortality after trauma; however, few studies have simultaneously investigated the association of depth of shock and acute hyperglycemia. We evaluated lactate, as a surrogate measure for depth of shock, and glucose levels […]

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Uncategorized Published - 14 April, 2021    By - Dr Clemens
Residual Neuromuscular Block Prediction Score Versus Train-of-Four Ratio and Respiratory Outcomes

AUTHORS: Patrocínio, Maria D. MD et al Anesthesia & Analgesia: January 22, 2021 – Volume – Issue – 10. BACKGROUND: Residual neuromuscular blockade is associated with an increased incidence of postoperative respiratory complications. The REsidual neuromuscular block Prediction Score (REPS) identifies patients at high risk for residual neuromuscular blockade after surgery. METHODS: A total of 101,510 […]

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