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Uncategorized Published - 21 April, 2021    By - Dr Clemens
Individualized versus Fixed Positive End-expiratory Pressure for Intraoperative Mechanical Ventilation in Obese Patients

Authors: Philipp Simon, M.D., Ph.D. et al Anesthesiology April 2021 Background General anesthesia may cause atelectasis and deterioration in oxygenation in obese patients. The authors hypothesized that individualized positive end-expiratory pressure (PEEP) improves intraoperative oxygenation and ventilation distribution compared to fixed PEEP. Methods This secondary analysis included all obese patients recruited at University Hospital of Leipzig […]

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Uncategorized Published - 21 April, 2021    By - Dr Clemens
Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Pain

Authors: Brian M. Ilfeld, M.D., M.S. et al  Anesthesiology April 2021. Background Percutaneous peripheral nerve stimulation is an analgesic technique involving the percutaneous implantation of a lead followed by the delivery of electric current using an external pulse generator. Percutaneous peripheral nerve stimulation has been used extensively for chronic pain, but only uncontrolled series have […]

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Uncategorized Published - 21 April, 2021    By - Dr Clemens
Perioperative Methadone and Ketamine for Postoperative Pain Control in Spinal Surgical Patients

Authors: Glenn S. Murphy, M.D. et al Anesthesiology May 2021, Vol. 134, 697–708. Background Despite application of multimodal pain management strategies, patients undergoing spinal fusion surgery frequently report severe postoperative pain. Methadone and ketamine, which are N-methyl-d-aspartate receptor antagonists, have been documented to facilitate postoperative pain control. This study therefore tested the primary hypothesis that patients […]

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Uncategorized Published - 21 April, 2021    By - Dr Clemens
Studies suggest link between ChAdOx1 nCov-19 vaccine and rare development of immune thrombotic thrombocytopenia

DG Alerts Study data published in The New England Journal of Medicine suggest that vaccination with ChAdOx1 nCov-19 (AstraZeneca) against coronavirus disease 2019 (COVID-19) can result in the rare development of immune thrombotic thrombocytopenia mediated by platelet-activating antibodies against platelet factor 4 (PF4), which clinically mimics autoimmune heparin-induced thrombocytopenia. A first study involved 11 patients in Germany and Austria […]

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Uncategorized Published - 20 April, 2021    By - Dr Clemens
Availability of Inpatient Pediatric Surgery in the United States

Authors: Michael L. McManus, M.D., M.P.H. et al Anesthesiology April 2021 Background In 2015, the American College of Surgeons began its Children’s Surgery Verification Quality Improvement Program, promulgating standards intended to promote regionalization and improve pediatric surgical care. It was hypothesized that pediatric surgical care was already highly regionalized and concentrated before implementation of the […]

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