AUTHORS: Baharloo, Raheleh MS et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1465-1474 BACKGROUND: Evidence suggests that increased early postoperative pain (POP) intensities are associated with increased pain in the weeks following surgery. However, it remains unclear which temporal aspects of this early POP relate to later pain experience. […]
Read MoreDG Journal Club AUTHORS: Go Otao, Toyoaki Maruta et al. Medicine (Baltimore). 2021 Apr 30; 100(17): e25560 ABSTRACT The aim of this study was to assess the efficacy of combined opioids by comparing four regimens of patient-controlled epidural analgesia (PCEA) after cesarean section.Parturient patients who underwent elective or emergent cesarean section under combined spinal and […]
Read MoreAUTHORS: Hsieh, Vincent C. MD et al Anesthesia & Analgesia: January 15, 2021 BACKGROUND: Children with mitochondrial disease undergo anesthesia for a wide array of surgical procedures. However, multiple medications used for their perioperative care can affect mitochondrial function. Defects in function of the mitochondrial electron transport chain (ETC) can lead to a profound hypersensitivity to […]
Read MoreAuthors: Kamal Maheshwari, M.D., M.P.H. et al Anesthesiology April 2021 Background Excessive or inadequate fluid administration causes complications, but despite this, fluid administration during noncardiac surgery is highly variable. Goal-directed management helps optimize the amount and timing of fluid administration; however, implementation is difficult because algorithms are complex. The authors therefore tested the performance of […]
Read MoreDG Journal Club Authors: Matthias Derwall, Mark Coburn Best Pract Res Clin Anaesthesiol. 2021 May; 35(1): 3-9 The clinical concept of frailty as a detectable and improvable clinical condition has emerged in the field of geriatric medicine over the past two decades. Albeit frailty can be described as the rapid deterioration of organ function during […]
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