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Uncategorized Published - 17 May, 2021    By - Dr Clemens
Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension in Intermediate- and High-risk Surgery

Authors: Alexandre Joosten, M.D., Ph.D. et al Anesthesiology May 2021. Background Individualized hemodynamic management during surgery relies on accurate titration of vasopressors and fluids. In this context, computer systems have been developed to assist anesthesia providers in delivering these interventions. This study tested the hypothesis that computer-assisted individualized hemodynamic management could reduce intraoperative hypotension in […]

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Uncategorized Published - 17 May, 2021    By - Dr Clemens
Automated Nerve Monitoring in Shoulder Arthroplasty

Authors: Jason Chui, M.B.Ch.B., M.Sc., F.A.N.Z.C.A., F.H.K.C.A., F.H.K.A.M. et al Anesthesiology April 2021. Background Evoked potential monitoring is believed to prevent neurologic injury in various surgical settings; however, its clinical effect has not been scrutinized. It was hypothesized that an automated nerve monitor can minimize intraoperative nerve injury and thereby improve clinical outcomes in patients […]

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Uncategorized Published - 17 May, 2021    By - Dr Clemens
Sevoflurane Exerts Protective Effects in Murine Peritonitis-induced Sepsis via Hypoxia-inducible Factor 1α/Adenosine A2B Receptor Signaling

Authors: Kristian-Christos Ngamsri, M.D. et al Anesthesiology April 2021 Background Sepsis is one of the leading causes of mortality in intensive care units, and sedation in the intensive care unit during sepsis is usually performed intravenously. The inhalative anesthetic sevoflurane has been shown to elicit protective effects in various inflammatory studies, but its role in […]

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Uncategorized Published - 17 May, 2021    By - Dr Clemens
Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice

Authors: Wenling Zhao, M.D. et al Anesthesiology May 2021. Background Isoflurane can induce anterograde amnesia. Hippocampal ripples are high-frequency oscillatory events occurring in the local field potentials of cornu ammonis 1 involved in memory processes. The authors hypothesized that isoflurane suppresses hippocampal ripples at a subanesthetic concentration by modulating the excitability of cornu ammonis 1 […]

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Uncategorized Published - 14 May, 2021    By - Dr Clemens
The Association of Dexmedetomidine on Perioperative Opioid Consumption in Children Undergoing Adenotonsillectomy With and Without Obstructive Sleep Apnea

AUTHORS: Adler, Adam C. MS, MD, FAAP, FASE et al Anesthesia & Analgesia: January 15, 2021 BACKGROUND: Dexmedetomidine is used to reduce opioid consumption in pediatric anesthesia. However, there is conflicting evidence in pediatric adenotonsillectomy literature regarding the total perioperative opioid-sparing effects of dexmedetomidine. The aim of this study was to examine the association between dexmedetomidine […]

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