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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Anesthesia for children with complete trisomy 18 (Edwards syndrome)

DG Journal Club AUTHORS: Erin E Birmingham, Astrid G Stucke et al. Paediatr Anaesth. 2021 Feb 28 BACKGROUND Trisomy 18 or Edwards syndrome is the second most common aneuploidy with a prevalence between 1/3000 and 1/10 000 live births. The syndrome encompasses malformations of the central nervous, cardiac, respiratory, gastrointestinal, and genitourinary systems. Trisomy 18 carries […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Evaluation of Drug Wastage in the Operating Rooms and Intensive Care Units of a Regional Health Service

AUTHORS: Barbariol, Federico MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1450-1456 BACKGROUND:  Pharmacological treatments for critical processes in patients need to be initiated as rapidly as possible; for this reason, it is a standard of care to prepare the main anesthesia and emergency drugs in advance. As […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Systematic review of outcomes and endpoints in acute migraine clinical trials

DG Journal Club AUTHORS: Carrie R Houts, James S McGinley et al. Headache. 2021 Feb; 61(2): 263-275 BACKGROUND/OBJECTIVE To review the acute migraine clinical trial literature and provide a summary of the endpoints and outcomes used in such trials. METHOD A systematic literature review, following a prespecified (but unregistered) protocol developed to adhere to recommendations […]

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Uncategorized Published - 19 May, 2021    By - Dr Clemens
Dimethyl Fumarate Reduces Oxidative Stress and Pronociceptive Immune Responses in a Murine Model of Complex Regional Pain Syndrome

AUTHORS: Guo, Tian-Zhi MD et al Anesthesia & Analgesia: May 2021 – Volume 132 – Issue 5 – p 1475-1485 BACKGROUND:  Complex regional pain syndrome (CRPS) is a highly disabling cause of pain often precipitated by surgery or trauma to a limb. Both innate and adaptive immunological changes contribute to this syndrome. Dimethyl fumarate (DMF) works […]

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Uncategorized Published - 18 May, 2021    By - Dr Clemens
Subcostal Anterior Quadratus Lumborum Block Versus Epidural Block for Analgesia in Open Nephrectomy

AUTHORS: Elsharkawy, Hesham MD, MBA, MSc, FASA et al Anesthesia & Analgesia: April 2021 – Volume 132 – Issue 4 – p 1138-1145 BACKGROUND:  Epidural block are often used for analgesia after open nephrectomy surgery. Subcostal anterior quadratus lumborum block may be an alternative. We therefore tested the hypothesis that the continuous subcostal anterior quadratus lumborum […]

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