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Uncategorized Published - 9 June, 2021    By - Dr Clemens
Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Pain

Authors: Brian M. Ilfeld, M.D., M.S. et al  Anesthesiology July 2021, Vol. 135, 95–110. Background Percutaneous peripheral nerve stimulation is an analgesic technique involving the percutaneous implantation of a lead followed by the delivery of electric current using an external pulse generator. Percutaneous peripheral nerve stimulation has been used extensively for chronic pain, but only […]

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Uncategorized Published - 9 June, 2021    By - Dr Clemens
Levels of Evidence Supporting the North American and European Perioperative Care Guidelines for Anesthesiologists between 2010 and 2020

Authors: Andres Laserna, M.D. et al  Anesthesiology July 2021, Vol. 135, 31–56. Background Although there are thousands of published recommendations in anesthesiology clinical practice guidelines, the extent to which these are supported by high levels of evidence is not known. This study hypothesized that most recommendations in clinical practice guidelines are supported by a low […]

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Uncategorized Published - 9 June, 2021    By - Dr Clemens
Anesthetic Considerations for Image-Guided Irreversible Electroporation

Authors: Ken Lee, MD et al  ASA Monitor June 2021, Vol. 85, 27–29. Irreversible electroporation (IRE) Irreversible electroporation (IRE) is an emerging non-thermal ablative technique with recent studies demonstrating its efficacy in destroying solid organ malignancies (Figure). The principle underlying IRE is applying sufficient electrical pulses to permanently increase cell membrane permeability. Subsequent formation of […]

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Uncategorized Published - 9 June, 2021    By - Dr Clemens
Innovative Procedures Outside the OR

Authors: Anahita Dabo-Trubelja, MD, FASA and Vijaya Gottumukkala, MBBS, MD, FRCA ASA Monitor June 2021, Vol. 85, 26–27. Innovations in imaging, technological advancements in micro-instrumentation, changing patient expectations and demands, and a general shift toward minimizing hospital stay are driving and expanding interventional radiology (IR) procedural growth as a more cost-effective acute care practice with positive impact […]

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Uncategorized Published - 9 June, 2021    By - Dr Clemens
Mitochondrial Function and Anesthetic Sensitivity in the Mouse Spinal Cord

Authors: Christian B. Woods, B.S. et al Anesthesiology June 2021, Vol. 134, 901–914. Background Ndufs4 knockout (KO) mice are defective in mitochondrial complex I function and hypersensitive to inhibition of spinal cord–mediated response to noxious stimuli by volatile anesthetics. It was hypothesized that, compared to wild-type, synaptic or intrinsic neuronal function is hypersensitive to isoflurane in […]

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