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Uncategorized Published - 28 June, 2021    By - Dr Clemens
Differential Perioperative Outcomes in Patients With Obstructive Sleep Apnea, Obesity, or a Combination of Both Undergoing Open Colectomy

AUTHORS: Stundner, Ottokar MD, MBA et al Anesthesia & Analgesia: June 2021 BACKGROUND: An increasing body of evidence demonstrates an association between obstructive sleep apnea (OSA) and adverse perioperative outcomes. However, large-scale data on open colectomies are lacking. Moreover, the interaction of obesity with OSA is unknown. This study examines the impact of OSA, obesity, or […]

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Uncategorized Published - 28 June, 2021    By - Dr Clemens
Intrathecal 2-Chloroprocaine 3% Versus Hyperbaric Bupivacaine 0.75% for Cervical Cerclage

AUTHORS: Lee, Allison MD, MS et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cervical cerclage is a short ambulatory procedure. For spinal anesthesia, local anesthetic agents with rapid postoperative resolution are desired. We hypothesized that in combination with fentanyl, intrathecal 2-chloroprocaine would produce earlier resolution of motor block, resulting in shorter time to meet recovery room […]

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Uncategorized Published - 28 June, 2021    By - Dr Clemens
P2Y1 Purinergic Receptor Contributes to Remifentanil-Induced Cold Hyperalgesia via Transient Receptor Potential Melastatin 8–Dependent Regulation of N-methyl-d-aspartate Receptor Phosphorylation in Dorsal Root Ganglion

AUTHORS: Su, Lin MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Remifentanil can induce postinfusion cold hyperalgesia. N-methyl-d-aspartate receptor (NMDAR) activation and upregulation of transient receptor potential melastatin 8 (TRPM8) membrane trafficking in dorsal root ganglion (DRG) are critical to cold hyperalgesia derived from neuropathic pain, and TRPM8 activation causes NMDAR-dependent cold response. Contribution of […]

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Uncategorized Published - 28 June, 2021    By - Dr Clemens
Outcome of Organ Dysfunction in the Perioperative Period

Authors: Thiele, Robert H. MD et al Anesthesia & Analgesia: June 2021 Abstract While intraoperative mortality has diminished greatly over the last several decades, the risk of death within 30 days of surgery remains stubbornly high and is ultimately related to perioperative organ failure. Perioperative strokes, while rare (<2% in noncardiac surgery), are associated with a […]

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Uncategorized Published - 28 June, 2021    By - Dr Clemens
Effect of Paratracheal Pressure on the Glottic View During Direct Laryngoscopy

AUTHORS: Won, Dongwook MD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Cricoid pressure has been used as a component of the rapid sequence induction and intubation technique. However, concerns have been raised regarding the effectiveness and safety of cricoid pressure. Paratracheal pressure, a potential alternative to cricoid pressure to prevent regurgitation of gastric contents or […]

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