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Uncategorized Published - 7 July, 2021    By - Dr Clemens
Pharmacotherapy for the Prevention of Chronic Pain after Surgery in Adults

Authors: Meg E. Carley, B.Sc. et al  Anesthesiology June 2021. Background Chronic postsurgical pain can severely impair patient health and quality of life. This systematic review update evaluated the effectiveness of systemic drugs to prevent chronic postsurgical pain. Methods The authors included double-blind, placebo-controlled, randomized controlled trials including adults that evaluated perioperative systemic drugs. Studies […]

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Uncategorized Published - 7 July, 2021    By - Dr Clemens
Automated Nerve Monitoring in Shoulder Arthroplasty: A Prospective Randomized Controlled Study

Authors: Jason Chui, M.B.Ch.B., M.Sc., F.A.N.Z.C.A., F.H.K.C.A., F.H.K.A.M. et al  Anesthesiology July 2021, Vol. 135, 83–94. Background Evoked potential monitoring is believed to prevent neurologic injury in various surgical settings; however, its clinical effect has not been scrutinized. It was hypothesized that an automated nerve monitor can minimize intraoperative nerve injury and thereby improve clinical […]

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Uncategorized Published - 7 July, 2021    By - Dr Clemens
Chronic Pain in Patients with Hemophilia: A Clinical Assessment and Treatment Primer

Author: Amanda Gerberich, PharmD, BCPS Practical Pain Management Volume 21 Issue 3 Hemophilia is a chromosomal disorder affecting coagulation that is characterized by spontaneous bleeding.1 The disorder affects approximately 1 in every 5,000 males. Hemophilia can be classified as a deficiency in clotting factor VIII (ie, hemophilia A), which is more common, or as a deficiency in […]

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Uncategorized Published - 7 July, 2021    By - Dr Clemens
Functional Profile of Systemic and Intrathecal Cebranopadol in Nonhuman Primates

Authors: Huiping Ding, Ph.D. et al  Anesthesiology June 2021. doi: Background Cebranopadol, a mixed nociceptin/opioid receptor full agonist, can effectively relieve pain in rodents and humans. However, it is unclear to what degree different opioid receptor subtypes contribute to its antinociception and whether cebranopadol lacks acute opioid-associated side effects in primates. The authors hypothesized that […]

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Uncategorized Published - 7 July, 2021    By - Dr Clemens
Data Builds the Case for Acupuncture in Pain Management

Author: Christine Rhodes, MS Practical Pain Management Volu 21 Issue 3 Acupuncture has been used for more than 2,000 years throughout Asia and is an important component of Traditional Chinese Medicine (TCM). Based on the concept of qi – the vital energy in the body that flows along well-defined meridians, acupuncture is thought to restore […]

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