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Uncategorized Published - 8 July, 2021    By - Dr Clemens
Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery

Authors: Ya-Wei Li, M.D. et al  Anesthesiology June 2021. Background Delirium is a common and serious postoperative complication, especially in the elderly. Epidural anesthesia may reduce delirium by improving analgesia, reducing opioid consumption, and blunting stress response to surgery. This trial therefore tested the hypothesis that combined epidural–general anesthesia reduces the incidence of postoperative delirium […]

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Uncategorized Published - 8 July, 2021    By - Dr Clemens
Patient Involvement in Anesthesia Decision-making: A Qualitative Study of Knee Arthroplasty

Authors: Veena Graff, M.D. et al  Anesthesiology July 2021, Vol. 135, 111–121. Background Calls to better involve patients in decisions about anesthesia—e.g., through shared decision-making—are intensifying. However, several features of anesthesia consultation make it unclear how patients should participate in decisions. Evaluating the feasibility and desirability of carrying out shared decision-making in anesthesia requires better […]

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Uncategorized Published - 8 July, 2021    By - Dr Clemens
Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain

Author: Keith M. Vogt, M.D., Ph.D. et al  Anesthesiology July 2021, Vol. 135, 69–82. Background Despite the well-known clinical effects of midazolam and ketamine, including sedation and memory impairment, the neural mechanisms of these distinct drugs in humans are incompletely understood. The authors hypothesized that both drugs would decrease recollection memory, task-related brain activity, and […]

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Uncategorized Published - 8 July, 2021    By - Dr Clemens
Anterior Quadratus Lumborum Block Does Not Provide Superior Pain Control after Hip Arthroscopy

Authors: Stephen C. Haskins, M.D. et al  Anesthesiology June 2021. Background Hip arthroscopy is associated with moderate to severe postoperative pain. This prospective, randomized, double-blinded study investigates the clinically analgesic effect of anterior quadratus lumborum block with multimodal analgesia compared to multimodal analgesia alone. The authors hypothesized that an anterior quadratus lumborum block with multimodal […]

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Uncategorized Published - 8 July, 2021    By - Dr Clemens
Utilizing CGRP Antagonists for Non-Migraine Indications

By Gerard Limerick, MD, PhD and Tina L. Doshi, MD, MHS Practical Pain Management Volume 21 Issue 3 The new class of CGRPs may also benefit patients living with chronic pain from trigeminal neuralgia, temporomandibular disorders, diabetic peripheral neuropathy, chemotherapy-induced neuropathy, and fibromyalgia. A review of the data to date. Calcitonin gene-related peptide (CGRP) antagonists have been a […]

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