AUTHORS: Kouz, Karim MD et al Anesthesia & Analgesia: August 2021 – Volume 133 – Issue 2 – p 406-412 BACKGROUND: It remains unknown what constitutes physiologically relevant intraoperative bradycardia. Intraoperative bradycardia is usually defined using absolute heart rate thresholds, ignoring preoperative baseline heart rates. In contrast, we considered defining intraoperative bradycardia relative to preoperative ambulatory […]
Read MoreAUTHORS: Ward, Andrew PhD et al Anesthesia & Analgesia: August 2021 – Volume 133 – Issue 2 – p 304-313 BACKGROUND: Long-term opioid use has negative health care consequences. Patients who undergo surgery are at risk for prolonged opioid use after surgery (POUS). While risk factors have been previously identified, no methods currently exist to determine […]
Read MoreAUTHORS: Hooten, W. Michael MD et al Anesthesia & Analgesia: June 2021 BACKGROUND: The adenosine triphosphate-binding cassette, subfamily B, member 1 gene (ABCB1) encodes P-glycoprotein (P-gp) that influences the intracellular transport of solutes including endogenous opioid peptides. The primary objective of this study was to determine the effects of the ABCB1 polymorphism c.3435C>T (rs10454642) on heat pain (HP) […]
Read MoreDG Journal Club AUTHORS: Johanna Margaretha Kroese, Sigvard Kopp et al. Clin Rheumatol. 2021 Jul 21 OBJECTIVES To evaluate the effect of corticosteroid injections in the painful temporomandibular joint (TMJ) of patients with rheumatoid arthritis (RA) in relation to systemic inflammatory activity. METHOD Examination of 35 patients (median age 54 years; 89% female) included maximum mouth […]
Read MoreAUTHORS: Kim, Hyunzu MD, PhD et al Anesthesia & Analgesia: June 2021 BACKGROUND: Relative to interscalene block, superior trunk block (STB) provides comparable analgesia and a reduced risk of hemidiaphragmatic paralysis. However, the incidence of hemidiaphragmatic paralysis remains high when a standard volume (15 mL) of local anesthetic is used. This study aimed to evaluate the […]
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