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Uncategorized Published - 12 August, 2021    By - Dr Clemens
Sleep apnea: Exercise and cutting TV time reduce risk

Author: Dale Kiefer Medical News Today Obstructive sleep apnea (OSA) is a sleep disorder that affects 10–20% of the adult population in the United States. OSA is associated with an increased risk of certain chronic diseases. A new study concludes that being more active and spending less time watching television are linked to a lower […]

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Uncategorized Published - 12 August, 2021    By - Dr Clemens
Study suggests post-COVID-19 neurological sequelae not accompanied by ongoing CNS injury

DG Alerts Normalisation of central nervous system (CNS) injury biomarkers in all individuals, regardless of previous disease severity or persisting neurological symptoms, indicates that post coronavirus disease 2019 (COVID-19) neurological sequelae are not accompanied by ongoing CNS injury, according to a study published in EBioMedicine. “To the best of our knowledge, this is the first study […]

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Uncategorized Published - 11 August, 2021    By - Dr Clemens
Comparative Study of Clinical and Ultrasound Parameters for Defining a Difficult Airway in Patients with Obesity

DG Journal Club AUTHORS Ed Carlos Rey Moura, Andrey Salgado Moraes Filho et al. Obes Surg. 2021 Jul 5 INTRODUCTION Patients with obesity have anatomical changes due to increased adipose tissue that negatively affect airway accessibility, making it difficult to establish an advanced airway through orotracheal intubation. This article aims to evaluate the correlation of […]

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Uncategorized Published - 11 August, 2021    By - Dr Clemens
Treating moderately ill COVID-19 patients with therapeutic-dose anticoagulation increased probability of survival but not for critically ill patients

DG Alerts Studies published in The New England Journal of Medicine showed that treating moderately ill hospitalised coronavirus disease 2019 (COVID-19) patients with therapeutic-dose anticoagulation with heparin increased the probability of survival to hospital discharge with reduced use of cardiovascular or respiratory organ support as compared with usual-care thromboprophylaxis. However, the use of this treatment strategy for […]

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Uncategorized Published - 11 August, 2021    By - Dr Clemens
Chiral Pharmacokinetics and Metabolite Profile of Prolonged-release Ketamine Tablets in Healthy Human Subjects

Authors: Mahmoud Hasan, Ph.D. et al  Anesthesiology August 2021, Vol. 135, 326–339. Background The anesthetic ketamine after intravenous dosing is nearly completely metabolized to R- and S-stereoisomers of the active norketamine (analgesic, psychoactive) and 2,6-hydroxynorketamine (potential analgesic, antidepressant) as well as the inactive dehydronorketamine. Oral administration favors the formation of 2,6-hydroxynorketamines via extensive presystemic metabolism. The authors […]

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