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Uncategorized Published - 23 August, 2021    By - Dr Clemens
Sleep apnea may almost double the risk of sudden death

Author: Leigh Ann Green Medical News today A new study investigates links between sleep apnea and cardiovascular-related deaths. no_limit_pictures/Getty Images Obstructive sleep apnea has become a worldwide health concern. Sleep apnea has associations with an increased risk of sudden and cardiovascular-related deaths. Future research should focus on decreasing and preventing this serious sleep condition. Obstructive […]

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Uncategorized Published - 23 August, 2021    By - Dr Clemens
Functional Profile of Systemic and Intrathecal Cebranopadol in Nonhuman Primates

Authors: Huiping Ding, Ph.D. et al  Anesthesiology September 2021, Vol. 135, 482–493. Background Cebranopadol, a mixed nociceptin/opioid receptor full agonist, can effectively relieve pain in rodents and humans. However, it is unclear to what degree different opioid receptor subtypes contribute to its antinociception and whether cebranopadol lacks acute opioid-associated side effects in primates. The authors […]

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Uncategorized Published - 20 August, 2021    By - Dr Clemens
Lidocaine infusions and reduced opioid consumption-Retrospective experience in pediatric hematology and oncology patients with refractory pain

DG Journal Club AUTHORS Doralina L Anghelescu, Kyle J Morgan et al. Pediatr Blood Cancer. 2021 Jul 15 BACKGROUND Despite a more robust experience with lidocaine infusions for pain management in adults and general pediatric population, there is limited evidence of efficacy of lidocaine infusions for pain management in patients with pediatric hematology and oncology […]

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Uncategorized Published - 20 August, 2021    By - Dr Clemens
Ibuprofen and COVID-19: Is it safe?

Author: Aaron Kadola Medical News Today Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It can reduce inflammation and ease several symptoms, including pain and fever. It is safe for people with COVID-19 to take — there is no evidence that ibuprofen increases the risk of harm from COVID-19 or the vaccines that protect against this […]

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Uncategorized Published - 20 August, 2021    By - Dr Clemens
How Pregabalin (LYRICA) Works?

Author: Cardiac Anesthesiologist Mechanism of action: Mechanism of action of pregabalin has not been exactly explained. It binds with high affinity to the alpha2-delta site – subunit of voltage-dependent calcium channels in central nervous system.Thus, calcium currents decrease, which may be associated with the antinociceptive and antiseizure effects of pregabalin. Nociception is the recognizing of painful stimuli.   What pregabalin is indicated for? Pregabalin […]

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