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DG Journal Club AUTHORS: Melissa M Masaracchia, Rani A Sunder et al. Paediatr Anaesth. 2021 Aug Ultrasound-guided nerve blocks have revolutionized the way we provide regional anesthesia. By providing effective perioperative pain control, regional anesthesia reduces opioid consumption, decreases length of stay, and increases patient/parental satisfaction. However, error traps (circumstances that lead to erroneous actions) […]
Read MoreAUTHORS: Ye, Yingchao MD et al Anesthesia & Analgesia: August 9, 2021 BACKGROUND: Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate–activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation and enhance reactive oxygen species (ROS) production. Apelin enhances […]
Read MoreAuthor: Cardiac anesthesiologist Most cardiac surgery (CS) programs mandate that a patient ingest nothing by mouth after midnight for surgery the following day, or at the very least, fast for 6 to 8 hours from the intake of a solid meal before elective cardiac surgery. Several randomized clinical trials have demonstrated, however, that nonalcoholic clear fluids […]
Read MoreAuthor: Cardiac Anesthesiologist Generally, in obese patients, the blood distributes more to nonadipose than to adipose tissues, resulting in higher plasma drug concentrations in obese patients with mg/kg dosing than in normal patients with less adipose mass. Furthermore, propofol clearance increases because of the increased liver volume and liver blood flow associated with obesity (and increased cardiac […]
Read MoreThis is for our readers who treat pain patients. Author: Jenna Fletcher Medical News Today Many preventive migraine medications exist. Some examples include angiotensin-converting enzyme (ACE) inhibitors, anticonvulsants, beta-blockers, and calcium channel blockers. Not every medication is right for every person, so individuals should always talk with a doctor to determine which migraine prevention method might work […]
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