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Uncategorized Published - 16 September, 2021    By - Dr Clemens
Over-Sedation in Patients With COVID-19, ARDS, Linked to Delirium Risk

By Nancy Melville DG News Critically-ill patients with coronavirus disease 2019 (COVID-19) and/or acute respiratory distress syndrome (ARDS) who are over-sedated are at an increased risk of delirium, regardless of their age, according to a study presented at the 40th International Symposium on Intensive Care and Emergency Medicine. “This study shows that, besides age, over-sedation […]

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Uncategorized Published - 16 September, 2021    By - Dr Clemens
Multiple sclerosis and back pain

Author: Adam Rowden MedicalNewsToday Multiple sclerosis (MS) is a condition that affects the central nervous system. It disrupts the flow of information between the brain and the rest of the body. In mild cases of MS, people can experience blurred vision, as well as numbness and tingling in the limbs. More severe cases can cause […]

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Uncategorized Published - 16 September, 2021    By - Dr Clemens
Apelin-13 Reverses Bupivacaine-Induced Cardiotoxicity via the Adenosine Monophosphate–Activated Protein Kinase Pathway

AUTHORS: Ye, Yingchao MD et al Anesthesia & Analgesia: August 9, 2021 – Volume – Issue – 10 BACKGROUND: Cardiotoxicity can be induced by the commonly used amide local anesthetic, bupivacaine. Bupivacaine can inhibit protein kinase B (AKT) phosphorylation and activated adenosine monophosphate–activated protein kinase alpha (AMPKα). It can decouple mitochondrial oxidative phosphorylation and enhance reactive […]

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Uncategorized Published - 15 September, 2021    By - Dr Clemens
Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium

AUTHORS: Wang, Man-Ling MD et al  Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 765-771 BACKGROUND:  Postoperative delirium is common among older surgical patients and may be associated with anesthetic management during the perioperative period. The aim of this study is to assess whether intravenous midazolam, a short-acting benzodiazepine used frequently […]

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Uncategorized Published - 15 September, 2021    By - Dr Clemens
Differential Perioperative Outcomes in Patients With Obstructive Sleep Apnea, Obesity, or a Combination of Both Undergoing Open Colectomy

AUTHORS: Stundner, Ottokar MD, MBA et al Anesthesia & Analgesia: September 2021 – Volume 133 – Issue 3 – p 755-764 BACKGROUND:  An increasing body of evidence demonstrates an association between obstructive sleep apnea (OSA) and adverse perioperative outcomes. However, large-scale data on open colectomies are lacking. Moreover, the interaction of obesity with OSA is unknown. […]

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