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AUTHORS: Uwe Reuter, John H Krege et al. Cephalalgia. 2021 Oct BACKGROUND A significant proportion of triptan users exhibit an insufficient response or inadequate tolerability to a triptan, and some may develop a contraindication. Lasmiditan, a selective 5-HT 1F receptor agonist, may be an option for these individuals. We assessed lasmiditan efficacy in a subgroup […]
Read MoreDG Journal Club Authors: Simone König, Christian Engl et al. J Pain. 2021 Oct In a previous study, we demonstrated that the serum peptidase system might be less efficient in complex regional pain syndrome (CRPS). Since the neuropeptide substanc P (SP) contributes to inflammation in CRPS, we now investigated the metabolism of SP in CRPS […]
Read MoreDG Journal Club Authors: Tyler C Lewis, Kimberly Sureau et al. Clin Transplant. 2021 Oct Opioid analgesics are commonly used post-lung transplant, but have many side effects and are associated with worse outcomes. We conducted a retrospective review of all lung transplant recipients who were treated with a multimodal opioid-sparing pain protocol. The use of […]
Read MoreDG Journal Club AUTHORS: Di Ye, Timothy J Fairchild et al. Diabet Med. 2021 Oct 21 AIMS Diabetic peripheral neuropathy (DPN) occurs in about half of people with diabetes, of whom a quarter may develop chronic pain. Pain may remain for years yet be difficult to treat because the underlying mechanisms remain unclear. There is […]
Read MoreAuthor: Erika Powers DG Alerts Among patients undergoing planned or emergency orthopaedic surgery, the rate of postoperative oxygen requirements, pneumonia, and mortality were significantly higher among those who had tested positive for coronavirus disease 2019 (COVID-19) within the 30 days prior to surgery than those without, according to a study presented at Anesthesiology 2021, the […]
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