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AUTHORS: Patel, Abhilasha MD et al Anesthesia & Analgesia: December 2021 BACKGROUND: Dysregulation of immune responses to surgical stress in older patients and those with frailty may manifest as differences in inflammatory biomarkers. We conducted a systematic review and meta-analysis to examine differences in perioperative inflammatory biomarkers between older and younger patients, and between patients with […]
Read MoreThis could be important when we use general anesthesia on post-acute COVID-19 patients. Findings from a study published in Annals of Clinical and Translational Neurology showed decreased gray matter (GM) volume and increased mean diffusivity (MD) in olfactory-related regions explaining prolonged olfactory deficits in post-acute coronavirus disease 2019 (COVID-19) patients.deficit is a frequent clinical manifestation of COVID-19; […]
Read MoreAuthor: Cardiac Anesthesiologist Until recently, parenteral opioids were the mainstay of postoperative pain management after Cardiac Surgery (CS). Opioids are associated with multiple adverse effects, including sedation, respiratory depression, nausea, vomiting, and ileus. There is growing evidence that multimodal opioid-sparing approaches can adequately address pain through the additive or synergistic effects of different types of analgesics, permitting […]
Read MoreAuthor: Саrdiac Anesthesiologist Prolonged mechanical ventilation after Cardiac Surgery (CS) is associated with longer hospitalization, higher morbidity, mortality, and increased costs. Prolonged intubation is associated with both ventilator-associated pneumonia and significant dysphagia. Early extubation, within 6 hours of ICU arrival, can be achieved with time-directed extubation protocols and low-dose opioid anesthesia. This is safe (even in patients at high risk) and associated with […]
Read MoreAUTHORS: Aykanat, Verna M. FANZCA, MBBS, BMedSci (Hons) et al Anesthesia & Analgesia: December 2021 BACKGROUND: Prevention of hypotension during the intra- and postoperative period is an important goal. Peripheral administration of low-concentration norepinephrine may be a safe and effective strategy to reduce the risk of hypotension. METHODS: We conducted a 2-center, randomized pilot feasibility trial, […]
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