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AUTHORS: Cozowicz, Crispiana MD et al Anesthesia & Analgesia: March 2022 – Volume 134 – Issue 3 – p 486-495 BACKGROUND: Despite numerous indications for perioperative benzodiazepine use, associated risks may be exacerbated in elderly and comorbid patients. In the absence of national utilization data, we aimed to describe utilization patterns using national claims data from […]
Read MoreAUTHORS: Zickerman, Caroline MD et al Anesthesia & Analgesia: February 2022 BACKGROUND: Postoperative negative behavioral changes (NBCs) are common among children, but risk for this is thought to be reduced with premedication. Midazolam has for many years been a standard premedication for children. More recently, the alpha-2 adrenergic agonist clonidine has also become popular as a […]
Read MoreDG Journal Club AUTHORS: Aymen A Al-Qurain, Richard N Upton et al. Eur J Drug Metab Pharmacokinet. 2022 Feb BACKGROUND AND OBJECTIVES Tramadol is commonly prescribed to manage chronic pain in older patients. However, there is a gap in the literature describing the pharmacokinetic parameters for tramadol and its active metabolite (O-desmethyltramadol [ODT]) in this […]
Read MoreAuthor: Annie Lennon MedicalNewsToday Researchers investigated how lower back pain interacts with eating behavior via behavioral and neuroimaging experiments. They found that pain alters food satiety in those who have chronic lower back pain and those who have recovered from subacute back pain. Further studies are necessary to understand the mechanisms behind their results. Studies […]
Read MoreDG News In a study of vaginal births in New York State hospitals, labour neuraxial analgesia was associated with a decreased risk of severe maternal morbidity. Deliveries with a neuraxial analgesia also lessened the risk of postpartum haemorrhage, the leading cause of preventable severe maternal morbidity, according to Jean Guglielminotti, MD, Columbia University Mailman School […]
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