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Authors: Ricardo Alvarez-Jimenez, M.D., Ph.D. et al Anesthesiology February 2022, Vol. 136, 279–292. Background Numerous pharmacokinetic models have been published aiming at more accurate and safer dosing of dexmedetomidine. The vast majority of the developed models underpredict the measured plasma concentrations with respect to the target concentration, especially at plasma concentrations higher than those used […]
Read MoreAuthors: David H. Kim, M.D. et al Anesthesiology March 2022, Vol. 136, 434–447. Background The interscalene nerve block provides analgesia for shoulder surgery. To extend block duration, provide adequate analgesia, and minimize opioid consumption, the use of adjuvants such as dexamethasone as well as the application of perineural liposomal bupivacaine have been proposed. This randomized, […]
Read MoreAuthors: Leopoldo V. Rodriguez, MD, MBA, FAAP, FASA, SAMBA-F et al ASA Monitor September 2021, Vol. 85, 25–26. There are over 5,800 Centers for Medicare & Medicaid Services (CMS)-certified ambulatory surgery centers (ASCs) in the United States, which are located in every state, each of which has its own laws and rules that govern ambulatory surgery […]
Read MoreAuthors: Michael A. Gropper, MD, PhD ASA Monitor October 2021, Vol. 85, 21–23. While it is impossible to predict the future of anesthesiology, we can learn much from current trends in perioperative care. Advances in technology are only part of the future. Perhaps more important than technology has been the recognition that all of our […]
Read MoreAuthors: Caleb Ing, M.D., M.S. et al Anesthesiology March 2022, Vol. 136, 500–512. Anesthetic agents disrupt neurodevelopment in animal models, but evidence in humans is mixed. The morphologic and behavioral changes observed across many species predicted that deficits should be seen in humans, but identifying a phenotype of injury in children has been challenging. It […]
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