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Uncategorized Published - 12 May, 2022    By - Dr Clemens
Vasopressor Effects on Cerebral Microcirculation: Comment

Authors: Anna Maria Bombardieri, M.D., Ph.D. and Ban C. H. Tsui, M.D., M.Sc. Anesthesiology May 2022, Vol. 136, 867–868. To the Editor: We read with great interest the study by Koch et al.,1  which concluded that “ephedrine results in better brain microcirculation and oxygen delivery than phenylephrine” and raised “concerns regarding phenylephrine for blood pressure augmentation in patients […]

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Uncategorized Published - 12 May, 2022    By - Dr Clemens
Vasopressor Effects on Cerebral Microcirculation: Reply

Authors: Klaus Ulrik Koch, M.D., Ph.D. and Mads Rasmussen, M.D., Ph.D. Anesthesiology May 2022, Vol. 136, 868. In Reply: We thank Bombardieri and Tsui1  for their excellent comments and interest in our study.2  We agree with Bombardieri and Tsui that the deterioration of microperfusion and possibly tissue oxygenation after phenylephrine administration in the “healthy” brain hemisphere2  indicates that different vasopressors […]

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Uncategorized Published - 11 May, 2022    By - Dr Clemens
Propofol-induced Unresponsiveness Is Associated with a Brain Network Phase Transition

Authors: Rebecca M. Pullon, Ph.D. et al  Anesthesiology March 2022, Vol. 136, 420–433. Background The wakeful brain can easily access and coordinate a large repertoire of different states—dynamics suggestive of “criticality.” Anesthesia causes loss of criticality at the level of electroencephalogram waveforms, but the criticality of brain network connectivity is less well studied. The authors […]

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Uncategorized Published - 11 May, 2022    By - Dr Clemens
Hyperoxia and Antioxidants for Myocardial Injury in Noncardiac Surgery: A 2 × 2

Authors: Cecilie Holse, M.D. et al  Anesthesiology March 2022, Vol. 136, 408–419. Background Hyperoxia and oxidative stress may be associated with increased risk of myocardial injury. The authors hypothesized that a perioperative inspiratory oxygen fraction of 0.80 versus 0.30 would increase the degree of myocardial injury within the first 3 days of surgery, and that an antioxidant […]

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Uncategorized Published - 11 May, 2022    By - Dr Clemens
Review of the ASA Physical Status Classification: Comment

Authors: Amr E. Abouleish, M.D., M.B.A. et al  Anesthesiology May 2022, Vol. 136, 864–865. To the Editor: We read with great interest the review article on the American Society of Anesthesiologists (ASA; Schaumburg, Illinois) Physical Status Classification System by Horvath et al. The review presents in excellent detail the origin, evolution, and current state of the ASA […]

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