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Uncategorized Published - 19 May, 2022    By - Dr Clemens
A Neural Circuit from the Paraventricular Thalamus to the Bed Nucleus of the Stria Terminalis for the Regulation of States of Consciousness during Sevoflurane Anesthesia in Mice

Authors: Jia-Yan Li, M.D., Ph.D. et al  Anesthesiology May 2022, Vol. 136, 709–731. Background The neural circuitry underlying sevoflurane-induced modulation of consciousness is poorly understood. This study hypothesized that the paraventricular thalamus bed nucleus of the stria terminalis pathway plays an important role in regulating states of consciousness during sevoflurane anesthesia. Methods Rabies virus–based transsynaptic tracing […]

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Uncategorized Published - 18 May, 2022    By - Dr Clemens
General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke

Authors: Axelle Maurice, M.D.et al  Anesthesiology April 2022, Vol. 136, 567–576. Background It is speculated that the anesthetic strategy during endovascular therapy for stroke may have an impact on the outcome of the patients. The authors hypothesized that conscious sedation is associated with a better functional outcome 3 months after endovascular therapy for the treatment of […]

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Uncategorized Published - 18 May, 2022    By - Dr Clemens
Limiting Oral Intake during Labor: Do We Have It Right?

Authors:Craig M. Palmer, M.D. and Yandong Jiang, M.D., Ph.D. Anesthesiology April 2022, Vol. 136, 528–530. “Is it time to rethink our current recommendations on oral intake during labor and delivery?” Limiting oral intake during labor is part of our standard orders for most parturients admitted to labor and delivery suites, but what exactly is the science that […]

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Uncategorized Published - 18 May, 2022    By - Dr Clemens
Basal Infusion versus Automated Boluses and a Delayed Start Timer for “Continuous” Sciatic Nerve Blocks after Ambulatory Foot and Ankle Surgery

Authors: John J. Finneran, IV, M.D. et al  Anesthesiology June 2022, Vol. 136, 970–982. Background The common technique using a basal infusion for an ambulatory continuous peripheral nerve blocks frequently results in exhaustion of the local anesthetic reservoir before resolution of surgical pain. This study was designed to improve and prolong analgesia by delaying initiation using […]

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Uncategorized Published - 18 May, 2022    By - Dr Clemens
Prophylactic Penehyclidine Inhalation for Prevention of Postoperative Pulmonary Complications in High-risk Patients

Authors: Ting Yan, M.D. et al  Anesthesiology April 2022, Vol. 136, 551–566. Background Postoperative pulmonary complications are common. Aging and respiratory disease provoke airway hyperresponsiveness, high-risk surgery induces diaphragmatic dysfunction, and general anesthesia contributes to atelectasis and peripheral airway injury. This study therefore tested the hypothesis that inhalation of penehyclidine, a long-acting muscarinic antagonist, reduces the […]

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