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Uncategorized Published - 6 June, 2022    By - Dr Clemens
Constrained Functional Connectivity Dynamics in Pediatric Surgical Patients Undergoing General Anesthesia

Authors: Michael P. Puglia, II, M.D., Ph.D. et al  Anesthesiology July 2022, Vol. 137, 28–40. Background Functional connectivity in cortical networks is thought to be important for consciousness and can be disrupted during the anesthetized state. Recent work in adults has revealed dynamic connectivity patterns during stable general anesthesia, but whether similar connectivity state transitions occur […]

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Uncategorized Published - 6 June, 2022    By - Dr Clemens
Targeting Depth of Anesthesia to Prevent Delirium: Comment

Authors: Xinglong Xiong, M.D. et al  Anesthesiology June 2022, Vol. 136, 1045–1046. To the Editor: Brown et al.1  nicely described their work comparing spinal anesthesia with targeted sedation based on Bispectral Index values compared with general anesthesia (masked Bispectral Index) and the outcome of delirium. Intraoperative hypotension has been associated with delirium.2,3  The adjusted hazard ratio associated with a […]

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Uncategorized Published - 6 June, 2022    By - Dr Clemens
Targeting Depth of Anesthesia to Prevent Delirium: Reply

Authors: Charles H. Brown, IV, M.D., M.H.S. Charles W. Hogue, M.D. Anesthesiology June 2022, Vol. 136, 1047–1048. In Reply: We thank Drs. Xiong et al.1  and Carella and Bonhomme2  for their comments regarding the shaping anesthetic techniques to reduce post-operative delirium (SHARP) study.3  We agree that evaluating intraoperative hypotension as a potentially moderating factor in the SHARP trial would be interesting. […]

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Uncategorized Published - 6 June, 2022    By - Dr Clemens
Targeting Depth of Anesthesia to Prevent Delirium: Comment

Authors: Michele Carella, M.D.; Vincent L. Bonhomme, M.D., Ph.D. Anesthesiology June 2022, Vol. 136, 1046–1047. To the Editor: We read with great interest the recent article by Brown et al.1  regarding the impact of Bispectral Index (BIS)–guided sedation on the incidence of postoperative delirium during spinal anesthesia for spine surgery compared with BIS-masked general anesthesia. We appreciated the originality […]

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Uncategorized Published - 6 June, 2022    By - Dr Clemens
Is your workplace hazardous to your health??

Author: Karen Sibert MD aPennedPoint I found myself on the wrong side of the ether screen earlier this year, having surgery on my left hand to release Dupuytren’s contracture, a genetic gift from my father and (maybe) generations of our Viking forebears. Wondering how long it will take to heal – and when I’ll get some […]

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