Edited by Melissa Warburg Medscape A recent phase 3 study of more than 800 adults, published in Nature, revealed encouraging results for a cannabis extract in treating chronic low back pain, offering new hope for patients seeking nonopioid relief. VER-01, a full-spectrum Cannabis sativa extract, provided sustained pain reduction while also improving sleep quality and physical function, and without requiring […]
Read MoreAuthors: Langer, Sarah et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005785 This meta-analysis of randomized controlled trials compared neonatal outcomes following cesarean delivery performed under regional anesthesia (spinal, epidural, or combined spinal-epidural) versus general anesthesia. Although regional techniques are widely preferred for maternal safety and recovery, their comparative effect on neonatal well-being has remained uncertain. […]
Read MoreAuthors: Padilla, Andrew et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005788 This multicenter retrospective cohort study examined anesthetic practices for cesarean hysterectomy in patients with placenta accreta spectrum (PAS) using data from the Multicenter Perioperative Outcomes Group (MPOG) database. Placenta accreta, increta, and percreta represent progressively invasive forms of abnormal placentation associated with massive hemorrhage […]
Read MoreAuthors: Wilson, Jenna et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005649 This prospective randomized controlled trial evaluated whether intraoperative ketamine reduces acute postsurgical pain in women undergoing breast cancer surgery, while also examining whether baseline temporal summation of pain (a measure of central sensitization) influences ketamine’s efficacy. A total of 225 patients were randomized to […]
Read MoreAuthors: Zhu, Youzhuang et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005800 This randomized controlled trial evaluated whether S-ketamine can reduce postoperative delirium (POD) in elderly patients undergoing total hip or knee arthroplasty under neuraxial anesthesia. The study enrolled 372 patients between November 2023 and October 2024 at a high-volume arthroplasty center with standardized perioperative care […]
Read More