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Published in Anesth Analg. 2014 May;118(5):946-55 Authors: Le Guen M et al., BACKGROUND: The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. METHODS: This double-blinded, randomized study […]
Read MorePublished in Allergol Int. 2014 Apr Authors: Saito M et al. Background: There are problems in diagnosis of allergy to amide-type local anesthetic agents (ALAs), because definitive diagnosis is not obtained by in vivo tests, which are used for the diagnosis. Consequently, patients may be exposed to risk. There are few diagnoses based […]
Read MoreAuthors: Abroug F and Krishnan JA., Am J Respir Crit Care Med 2014 May 1; 189:1014 Patients with chronic obstructive pulmonary disease exacerbations who require intensive care admission do better with low-dose steroids. A 2010 observational study suggested that relatively low-dose oral corticosteroids were as good as — or better than — high-dose parenteral steroids […]
Read MoreAuthors: Donnino MW et al., Crit Care Med 2014 Apr 25; Lower lactate levels and more rapid lactate clearance were associated with improved survival and good neurologic outcomes. Although guidelines recommend serial lactate measurements to assess perfusion in critically ill patients, data to support this approach are derived mainly from burn, trauma, and septic patients […]
Read MoreAuthors: Clarke H et al., BMJ 2014 Feb 11; 348:g1251 A small but substantial percentage of opiate-naïve patients were still taking pain medications 90 days after major surgery. Annually, more than 200 million patients undergo major surgery worldwide. Many patients require treatment with opiates for moderate-to-severe postoperative pain; most quickly transition off of pain medications. […]
Read MorePublished in Arch Pediatr. 2014 Apr Authors: Walter-Nicolet E et al., Abstract Tracheal intubation in neonates is a painful procedure performed daily in the delivery room despite the widespread development of noninvasive ventilation. Specific analgesia is not commonly performed. The objective of this observational study was to compare practices between two level-III centers: […]
Read MoreThe purchase of Health Management Associates by Community Health Systems for $7.6 billion and the sale of Vanguard Health Systems to Tenet Healthcare for $4.3 billion were healthcare’s two largest deals last year. Hospital mergers and acquisitions in the United States declined in 2013, but the number of hospitals and hospital beds involved in those […]
Read MorePublished in Paediatr Anaesth. 2014 Jun;24(6):614-9 Authors: Bortone L et al., BACKGROUND: Early negative postoperative behavior (e-PONB) is common in children and manifests itself as emergence agitation (EA), emergence delirium (ED), and pain. The objective of this prospective double blind, randomized, placebo-controlled trial was to determine whether IV clonidine or IV fentanyl prior to […]
Read MoreMore than 1 million patients who use federally funded community health centers will remain uninsured because they live in 24 states that chose not to expand Medicaid under the Affordable Care Act, according to a study released Friday by researchers at George Washington University. Most of those patients live in the South, because every state […]
Read MoreThis is written by Jennifer Gunter an obstetrician-gynecologist and author of The Preemie Primer. She blogs at her self-titled site, Dr. Jen Gunter. Reports that Mila Kunis, the actress, plans on a “natural” delivery is all over the Internet. As a celebrity she is clearly a medical expert and somehow it is relevant to hear […]
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