Author: Dr Clemens

Uncategorized Published - 11 November, 2019    By - Dr Clemens
Patient and System Factors Affecting Anesthesiologist First Case Start Performance

Authors: George Hoffman, M.D. et al Introduction: Performance of anesthesiologists, surgical teams, and perioperative systems is commonly measured by the percent of first case on time start (FCOTS) as percent of first cases of the day (FCOD) and by first case start delay (FCSD) time. Although these metrics have reported variable relationships to other measures […]

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Uncategorized Published - 8 November, 2019    By - Dr Clemens
Preoperative Blood Pressure Complexity Indices as a Marker for Frailty in Patients Undergoing Cardiac Surgery

Authors: Valluvan Rangasamy, MD, DESA  et al Journal of Cardiothoracic and Vascular Anesthesia Oct 2019 Objective Frailty, a state of decreased physiological reserve, increases the risk of adverse outcomes. There is no standard tool for frailty during perioperative period. Autonomic dysfunction, an underlying process in frailty, could result in hemodynamic fluctuations. Complexity, the physiological adaptability […]

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Uncategorized Published - 8 November, 2019    By - Dr Clemens
The influence of time to surgery on mortality after a hip fracture

Authors: Johan Kristiansson et al Anaesthesiologica Scandinavica Oct 2019 Background The effect of time‐to‐surgery on mortality in acute hip fracture (AHF) patients has been debated and studies are inconsistent regarding from what time‐limit mortality starts to increase. At Sahlgrenska University Hospital/Mölndal, surgery is recommended within 24 hours leaving little time for preoperative optimisation. However, internationally […]

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Uncategorized Published - 8 November, 2019    By - Dr Clemens
Investigational Capsaicin Therapy After Bunionectomy Reduces Pain, Opioid Reliance

Author: Bob Kronemyer Anesthesiology News The novel, water-soluble prodrug CA-008 (Concentric Analgesics), coupled with standard of care treatment that included a Mayo block with bupivacaine hydrochloride (HCl), was found to significantly reduce both pain and opioid reliance after bunionectomy surgery, according to two randomized, placebo-controlled studies. “CA-008 is a prodrug of trans-capsaicin, the substance in […]

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Uncategorized Published - 8 November, 2019    By - Dr Clemens
Ketamine Administration During Hospitalization Is Not Associated With Posttraumatic Stress Disorder Outcomes in Military Combat Casualties

AUTHORS: Highland, Krista B. PhD et al Anesthesia & Analgesia: July 17, 2019 BACKGROUND: Ketamine is routinely used within the context of combat casualty care. Despite early concerns that ketamine administration may be associated with elevated risk of posttraumatic stress disorder (PTSD), more recent evidence suggests no relationship. Because PTSD occurs with regular frequency in Operation Iraqi […]

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Uncategorized Published - 8 November, 2019    By - Dr Clemens
Pain Management Protocol Sends 92% of Patients Home Without Opioids After Cancer Surgery

A specialised pain management program for patients who underwent robotic surgery for urologic cancers resulted in just 8% going home with narcotics after discharge, compared with 100% who would have received them without this enhanced recovery protocol. What’s more, the group of patients who did receive narcotics went home with fewer medications than they would […]

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Uncategorized Published - 7 November, 2019    By - Dr Clemens
Marginal Improvement in Survival Post-Heart Transplantation in Patients With Prior Left Ventricular Assist Device

AUTHORS: Nirvik Pal, MD et al Journal of Cardiothoracic and Vascular Anesthesia Objective An increasing number of patients undergoing heart transplantation are being bridged with left ventricular assist devices (LVADs). Bridge-to-transplantation (BTT) LVAD has improved wait list survival remarkably. Historically, post-heart transplantation survival in BTT-LVAD patients, however, has remained inferior to that of primary heart […]

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Uncategorized Published - 7 November, 2019    By - Dr Clemens
Use of ultrasound-measured internal jugular vein collapsibility index to determine static intracardiac pressures in patients with presumed pulmonary hypertension

Authors: aj Parikh et al Annals of Intensive Care volume 9, Article number: 124 (2019) Background Bedside ultrasound helps to estimate volume status in critically ill patients and has traditionally relied on diameter, respiratory variation, and collapsibility of the inferior vena cava (IVC) to reflect fluid status. We evaluated collapsibility of the internal jugular vein (IJ) with ultrasound and correlated […]

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Uncategorized Published - 7 November, 2019    By - Dr Clemens
Sevoflurane but Not Propofol Modulates Breast Cancer Cell Survival via Interaction with the Trpv1 Calcium Channel

Authors: Huafeng Wei, M.D.,Ph.D. et al Anesthesiology 2019 We compared the effects and mechanisms of sevoflurane vs. propofol at equipotent dose (1 MAC vs 2 µM) on cell survival, proliferation and migration, intracellular calcium homeostasis in different types of human breast normal or cancer cells. Methods We used estrogen receptor positive (MCF7) and estrogen receptor […]

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Uncategorized Published - 7 November, 2019    By - Dr Clemens
Common Antidepressants Interact With Tramadol to Lessen Pain Relief

Common antidepressants interact with tramadol to make it less effective for pain relief, according to a study published in Pharmacotherapy. The findings have important implications for the opioid epidemic, suggesting that some patients suspected of drug-seeking may in fact be under-medicated and just are seeking more effective pain relief. The results of the study could also […]

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