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DG Alerts The US Food and Drug Administration (FDA) has approved oliceridine (Olinvyk), an opioid agonist, for the management of moderate-to-severe acute pain in adults, where the pain is severe enough to require an intravenous (IV) opioid and for whom alternative treatments are inadequate. Oliceridine is indicated for short-term IV use in hospitals or other […]
Read MoreDG Alerts Findings from a UK study published in The Lancet Oncology indicate that cancer patients with different tumour types have variable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) susceptibility and coronavirus disease 2019 (COVID-19) phenotypes. In particular, patients with haematological cancers (leukaemia, lymphoma, or myeloma) had increased susceptibility to the virus, and were at greater risk […]
Read MoreDG Alerts According to data from an open-label Phase III study published in the Journal of the American Medical Association, patients with moderate coronavirus disease 2019 (COVID-19) pneumonia randomized to receive remdesivir treatment for up to 5 days had significantly higher odds of achieving clinical improvement at the 11-day mark than those receiving standard care. However, […]
Read MoreAuthor: Michael Walter Cardiovascular Business News Antihypertensive medications can improve COVID-19 survival rates and reduce the likelihood of severe illness, according to a new meta-analysis published in Current Atherosclerosis Reports. The study’s authors explored data from 19 different studies, focusing on the impact of renin-angiotensin-aldosterone system (RAAS) inhibitors such as angiotensin-converting enzyme inhibitors (ACEi) and angiotensin-receptor […]
Read MoreI want to thank all of our readers a fun and happy labor day. Please be safe
Read MoreAuthor: Michael Walter Cardiovascular Business News Blood pressure variability (BPV) from one visit to the next is associated with cognitive decline and even dementia, according to a new study published in Hypertension. “The clinical relevance of BPV has not been considered until recently,” wrote lead author Laure Rouch, PhD, PharmD, Paris Descartes University in France, […]
Read MoreAuthor: Michael Walter Cardiovascular Business News Researchers in Sweden believe they may have identified a primary reason so many COVID-19 patients suffer from thrombosis, sharing their findings in Thrombosis and Haemostasis. The team’s discovery revolves around mannose-binding lectin (MBL), a protein that is part of the body’s natural immune system. Exploring data from 65 patients who […]
Read MoreDG Alerts A research letter published online in the Annals of the American Thoracic Society concluded that asthma may be an overestimated risk factor for hospitalisation due to coronavirus disease 2019 (COVID-19). Richard Broadhurst, University of Colorado Anschutz Medical Campus, Aurora, Colorado, and colleagues compared the prevalence of asthma among patients hospitalised for COVID-19, as reported in […]
Read MoreDG Alerts Researchers have identified a mechanism they believe explains why so many critically ill patients with coronavirus disease 2019 (COVID-19) have an increased risk of thromboembolic complications despite pharmacological thromboprophylaxis. In a cohort of 65 patients with severe COVID-19 in intensive care, Oskar Eriksson, MD, University Hospital, and Uppsala University, Uppsala, Sweden, and colleagues […]
Read MoreAuthors: Victor G. B. Liem, M.D., M.Sc. et al Anesthesiology 9 2020, Vol.133, 510-522. Background: Intraoperative hypotension has been associated with postoperative morbidity and early mortality. Postoperative hypotension, however, has been less studied. This study examines postoperative hypotension, hypothesizing that both the degree of hypotension severity and longer durations would be associated with myocardial injury.Methods: This single-center observational […]
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