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DG Journal Club AUTHORS Mircea Iftinca, Manon Defaye et al. Drugs. 2020 Nov 9 The transient receptor potential vanilloid-1 (TRPV1) is a non-specific cation channel known for its sensitivity to pungent vanilloid compound (i.e. capsaicin) and noxious stimuli, including heat, low pH or inflammatory mediators. TRPV1 is found in the somatosensory system, particularly primary afferent […]
Read MoreAuthor: Michael Walter Cardiovascular Business News A whopping 93% of adult patients with type 2 diabetes (T2D) are at a high risk of experiencing a fatal acute myocardial infarction (AMI) or stroke, according to new research published in the European Journal of Preventive Cardiology. The study was focused on data out of Catalonia, Spain, but its findings […]
Read MoreBy Akshay Syal and Sara G. Miller NBC Health Health care personnel and residents of long-term care facilities will be the first groups to be offered the Covid-19 vaccine, according to a new proposal from an independent advisory committee within the Centers for Disease Control and Prevention. The Advisory Committee on Immunization Practices met virtually on Tuesday to […]
Read MoreDG Alerts Adult outpatients with symptomatic coronavirus disease 2019 (COVID-19) treated with fluvoxamine, compared with placebo, had a lower likelihood of clinical deterioration over 15 days, according to a preliminary study published in the Journal of the American Medical Association. However, the researchers led by Eric J Lenze, MD, Washington University in St Louis, St Louis, […]
Read MoreAuthor: Denise Baez DG Alerts Patients with multiple myeloma who were hospitalised with coronavirus disease 2019 (COVID-19) had a high mortality rate, with significant geographic variability, ranging from 27% to 57%, according to the first results from the International Multiple Myeloma COVID-19 dataset, published in the journal Blood. The International Multiple Myeloma COVID-19 dataset, created by […]
Read MoreMedical X press Low-frequency spinal cord stimulation (SCS) may be effective for treating painful diabetic neuropathy (DN), according to a study scheduled for presentation at the 19th Annual Pain Medicine Meeting, a meeting of the American Society of Regional Anesthesia and Pain Medicine, held virtually from Nov. 20 to 22. Erika Petersen, M.D., from the […]
Read MoreThe Neurobics Randomized Clinical Trial Authors: Michelle L. Humeidan, MD, PhD et al JAMA Surg. November 2020. Key PointsQuestion Does preoperative cognitive exercise reduce the incidence of postoperative delirium in older adults undergoing major noncardiac surgery? Findings Results of this randomized clinical trial show patients who met at least minimum compliance with a preoperative cognitive exercise intervention […]
Read MoreAUTHORS: Varsha Alex, Sumit R Singh et al. Retina. 2020 Oct 28 PURPOSE Lidocaine gel was suggested to be highly effective in providing anesthesia for intravitreal injections but adverse effects include possibility of making sterilization of the conjunctiva difficult. Hence, we wished to determine the effect of using 0.5% proparacaine drops alone over the use […]
Read MoreDG Alerts The combination of myocardial injury with high-sensitivity cardiac troponin T (hs-cTnT) levels ≥ 20 ng/L, plus cardiac conduction perturbations, especially atrial fibrillation or atrial flutter (AF/AFL), upon hospital admission for coronavirus disease 2019 (COVID-19) is associated with “markedly increased” risk for mortality than either diagnostic abnormality alone, according to a study published in the Journal of the American Heart […]
Read MoreAuthors: Michael Walter Cardiovascular Business News Myocarditis could be much more rare among COVID-19 patients than researchers previously predicted, according to new findings published in Cardiovascular Pathology. The authors reviewed data from 22 different studies, tracking findings related to the autopsied hearts of a total of 277 COVID-19 patients. The average patient age was 75 years […]
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