Author: Dr Clemens

Uncategorized Published - 28 October, 2025    By - Dr Clemens
Remimazolam vs. dexmedetomidine for postoperative sedation in oral tumor patients undergoing free flap reconstruction

Authors: Yun Liu et al BMC Anesthesiology, 2025; Article 483. Volume 25, 2025 This randomized, double-blind clinical trial compared remimazolam and dexmedetomidine for postoperative sedation following free-flap reconstruction in patients with oral tumors—a surgical population requiring stable hemodynamics and smooth emergence to protect delicate microvascular anastomoses. Although dexmedetomidine is widely used for sedation, remimazolam’s rapid […]

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Uncategorized Published - 28 October, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 27 October, 2025    By - Dr Clemens
The Role of Delta-Opioid Receptor in Mediating the Cardioprotective Effects of Morphine Preconditioning via the JAK2/STAT3 Pathway in a Failing Heart

Authors: Pan X. et al. Anesthesia & Analgesia, October 2025. DOI: 10.1213/ANE.0000000000007290 This translational study investigated the role of delta-opioid receptor (DOR) signaling in myocardial protection during ischemia/reperfusion (I/R) injury in the setting of chronic heart failure. Patients with heart failure are highly susceptible to perioperative myocardial damage, and evidence from animal models has implicated […]

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Uncategorized Published - 27 October, 2025    By - Dr Clemens
Trends in Use of Medications for Opioid Use Disorder among Commercially Insured U.S. Surgical Patients, 2016-2022

Authors: Bicket M.C. et al. Anesthesiology, September 25, 2025. DOI: 10.1097/ALN.0000000000005771 This large national cohort study evaluated trends in the use of medications for opioid use disorder (MOUD) among commercially insured adults undergoing major surgical procedures in the United States between 2016 and 2022. As the number of surgical patients treated with MOUD continues to […]

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Uncategorized Published - 27 October, 2025    By - Dr Clemens
Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC)

Authors: Shen F. et al. Anesthesiology, October 14, 2025. DOI: 10.1097/ALN.0000000000005707 This multicenter randomized clinical trial (AmPRAEC study) evaluated whether different anesthesia maintenance strategies influence postoperative respiratory adverse events (PRAEs) in children undergoing adenotonsillectomy. Conducted across 12 hospitals in China, the trial enrolled 760 pediatric patients aged 0 to 12 years who were randomly assigned […]

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Anesthesiology Published - 27 October, 2025    By - Dr Clemens
40 Years of Progress and Future Directions in Chronic Pain Management and Patient Safety

Authors: Steven P. Cohen, MD; Leena Mathew, MD; Stephanie G. Vanterpool, MD, MBA; Amy C.S. Pearson, MD Anesthesia Patient Safety Foundation Vo; 40 No 3 Oct 2025 Summary:Over four decades, chronic pain management has advanced through interventional techniques, safer pharmacologic practices, and multidisciplinary care. Key challenges remain, including opioid misuse, patient variability, and ensuring equitable […]

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Uncategorized Published - 27 October, 2025    By - Dr Clemens
How ASCs will evolve by 2030

Author: Patsy Newitt Becker’s ASC Review Leaders say the next five years will bring a sharper, smarter ASC industry, one that is more data-driven, integrated and patient-focused. Six ASC leaders joined Becker’s to discuss how they see the ASC industry evolving over the next five years. Editor’s note: Responses have been lightly edited for clarity and length.  […]

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Uncategorized Published - 27 October, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 24 October, 2025    By - Dr Clemens
Effect of S-Ketamine on Postoperative Delirium in Elderly Patients Undergoing Arthroplasty

Authors: Zhu Y. et al. Anesthesiology, October 14, 2025. DOI: 10.1097/ALN.0000000000005800 This randomized controlled trial investigated whether S-ketamine reduces postoperative delirium (POD) in elderly patients undergoing total hip or knee arthroplasty under neuraxial anesthesia—avoiding the potential confounding effects of general anesthesia on ketamine’s neuroprotective properties. Conducted at a high-volume arthroplasty center with rigorous perioperative standardization, […]

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Uncategorized Published - 24 October, 2025    By - Dr Clemens
Bispectral Index–Guided Anesthesia for Older Patients Having Non-Cardiac Surgery

Authors: Zhou L. et al. Anesthesiology, September 25, 2025. DOI: 10.1097/ALN.0000000000005770 This large randomized multicenter trial investigated whether Bispectral Index (BIS)–guided anesthesia improves postoperative outcomes in older adults undergoing elective noncardiac surgery. Although BIS monitoring has been recommended in several perioperative guidelines to help maintain optimal anesthetic depth and potentially reduce complications, strong evidence supporting […]

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