Author: Dr Clemens

Anesthesiology Published - 15 January, 2026    By - Dr Clemens
Why ASC ownership is getting more complicated

Author: Patsy Newitt Becker’s ASC Review As private equity, MSOs and hospitals continue to expand their presence in ASCs, ownership models are becoming more complex. Tina DiMarino, CEO of Custom Surgical Partners, joined Becker’s to discuss how joint ventures, specialty rollups and increased investor activity are reshaping the ASC landscape. Custom Surgical Partners, an ASC development company […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Pharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass

Authors: Beukers A et al. Anesthesia & Analgesia, Volume 142, Issue 1, pages 5–14, January 2026 Summary:This narrative review synthesizes how cardiopulmonary bypass (CPB) alters the pharmacokinetics (PK) and pharmacodynamics (PD) of commonly used continuously administered anesthetic and analgesic drugs during on-pump cardiac surgery, and why those shifts can translate into clinically meaningful under- or […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Intrathecal Hydromorphone Versus Intrathecal Morphine for Postcesarean Delivery Analgesia

Authors: Cheng S et al. Anesthesia & Analgesia, Volume 142, Issue 1, pages 19–27, January 2026 Summary:This randomized, blinded noninferiority trial evaluated whether intrathecal hydromorphone is noninferior to intrathecal morphine for postcesarean delivery analgesia when both are administered at their previously established ED90 doses. Given ongoing concerns regarding morphine-related side effects and intermittent drug shortages, […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Spectral Differences of Anesthetic Agents: Addressing Fundamental Problems With New Methods

Authors: Dragovic SZ et al. Anesthesia & Analgesia, Volume 142, Issue 2, pages 249–260, February 2026 Summary:This retrospective study examines whether commonly used processed EEG metrics obscure meaningful differences between anesthetic agents, particularly propofol versus volatile fluranes (sevoflurane and desflurane). The authors challenge the “one-size-fits-all” assumption that equivalent processed EEG targets reflect comparable anesthetic brain […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Efficacy and Safety of Preemptive Magnesium Sulfate Infusion during Pheochromocytoma and Paraganglioma Resection

Authors: Kong H et al. Journal: Anesthesiology, November 25, 2025. DOI: 10.1097/ALN.0000000000005778 SummaryThis randomized, double-blind, placebo-controlled trial evaluated whether preemptive magnesium sulfate infusion improves intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—procedures well known for extreme catecholamine-mediated blood pressure and heart rate fluctuations. Ninety-two patients scheduled for PPGL resection were randomized to receive either […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
The anesthesia breakthroughs that defined 2025

Author: Sophie Eydis Becker’s ASC Review Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to next-generation pain control, five breakthroughs in particular helped shape the specialty. 1. AI-driven decision support, smart ultrasound and virtual reality-enhanced training […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Cardiac Biomarkers and Risk Stratification in Liver Transplantation for Acute-on-chronic Liver Failure: Refining Current Risk Models for Improved Prediction of Posttransplant Mortality

Authors: Kwon H-M et al. Journal: Anesthesiology, December 2, 2025. DOI: 10.1097/ALN.0000000000005747 SummaryThis retrospective registry-based study evaluated whether incorporating cardiac biomarkers into existing risk models improves prediction of post–liver transplant mortality in patients with acute-on-chronic liver failure (ACLF). Cardiovascular complications are the leading cause of death after liver transplantation in this population, yet commonly used […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks

Authors: Turan A et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005869 SummaryThis multicenter randomized controlled trial (the CLEVELAND Trial) evaluated whether liposomal bupivacaine provides superior or prolonged analgesia compared with plain bupivacaine or saline when used in single-injection, four-quadrant transversus abdominis plane (TAP) blocks for major abdominal surgery. Given widespread use of liposomal bupivacaine […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index

Authors: Hussain N et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005876 SummaryThis systematic review evaluated the statistical robustness of randomized controlled trials assessing spinal cord stimulation (SCS for chronic pain using the fragility index (FI). While SCS has gained wide adoption based on statistically significant trial outcomes, the fragility index provides a complementary lens […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
The role of the dorsomedial periaqueductal gray glutamatergic neurons in promoting arousal under multiple general anesthetics in mice

Authors: Tong L et al. Journal: Anesthesiology, December 15, 2025. DOI: 10.1097/ALN.0000000000005903 SummaryThis preclinical study investigated the role of glutamatergic neurons in the dorsomedial periaqueductal gray (dmPAG) as a shared neural substrate regulating arousal and emergence across multiple general anesthetics. Although general anesthetics differ in molecular targets, the authors hypothesized that convergent brainstem circuitry may […]

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