Author: Dr Clemens

Uncategorized Published - 8 February, 2021    By - Dr Clemens
The Perioperative Implementation of a Hypertension Protocol by Anesthesiologists

AUTHORS: Pfister, Claire-Louise MBChB, BSc, DA, DCH et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1401-1408 BACKGROUND:  Hypertension is a common risk factor for cardiovascular morbidity and mortality, with a high prevalence in patients presenting for elective surgery. In limited resource environments, patients have poor access to primary […]

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Uncategorized Published - 8 February, 2021    By - Dr Clemens
Study suggests microthrombi is a major cause of cardiac injury in COVID-19

DG Alerts An autopsy study published in Circulation finds that 35% of patients dying with coronavirus disease 2019 (COVID-19) had evidence of cardiac injury identified by the presence of myocyte necrosis, while the most common pathologic cause of myocyte necrosis was microthrombi. “Cardiac injury is common in hospitalised patients with COVID-19 and portends poorer prognosis. However, the […]

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Uncategorized Published - 8 February, 2021    By - Dr Clemens
Neither Preoperative Pulse Pressure nor Systolic Blood Pressure Is Associated With Cardiac Complications After Coronary Artery Bypass Grafting

AUTHORS: Zhang, Kan MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1491-1499 BACKGROUND:  Increased pulse pressure has been associated with adverse cardiovascular events, cardiac and all-cause mortality in surgical and nonsurgical patients. Whether increased pulse pressure worsens myocardial injury and dysfunction after cardiac surgery, however, has not […]

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Uncategorized Published - 8 February, 2021    By - Dr Clemens
Effect of Perioperative Active Body Surface Warming Systems on Analgesic and Clinical Outcomes

AUTHORS: Balki, Indranil HBSc, MD Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1430-1443 BACKGROUND:  Inadvertent perioperative hypothermia is a common complication of surgery, and active body surface warming (ABSW) systems are used to prevent adverse clinical outcomes. Prior data on certain outcomes are equivocal (ie, blood loss) or limited (ie, […]

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Uncategorized Published - 8 February, 2021    By - Dr Clemens
The Performance of an Artificial Neural Network Model in Predicting the Early Distribution Kinetics of Propofol in Morbidly Obese and Lean Subjects

AUTHORS: Ingrande, Jerry MD, MS et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1500-1509 BACKGROUND:  Induction of anesthesia is a phase characterized by rapid changes in both drug concentration and drug effect. Conventional mammillary compartmental models are limited in their ability to accurately describe the early drug distribution […]

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Uncategorized Published - 5 February, 2021    By - Dr Clemens
Thromboelastographic Assessment of Fibrinolytic Activity in Postpartum Hemorrhage

AUTHORS: Arnolds, David E. MD, PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1373-1379 BACKGROUND:  Postpartum hemorrhage is a leading cause of maternal mortality. Antifibrinolytic therapy has the potential to influence outcomes in postpartum hemorrhage, but the incidence of elevated fibrinolytic activity in postpartum hemorrhage is unknown. […]

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Uncategorized Published - 5 February, 2021    By - Dr Clemens
Influence of Levobupivacaine Regional Scalp Block on Hemodynamic Stability, Intra- and Postoperative Opioid Consumption in Supratentorial Craniotomies

AUTHORS: Carella, Michele MD et al Anesthesia & Analgesia: February 2021 – Volume 132 – Issue 2 – p 500-511 BACKGROUND:  The anesthetic management of supratentorial craniotomy (CR) necessitates tight intraoperative hemodynamic control. This type of surgery may also be associated with substantial postoperative pain. We aimed at evaluating the influence of regional scalp block […]

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Uncategorized Published - 5 February, 2021    By - Dr Clemens
Atrial fibrillation is an independent predictor for in-hospital mortality in patients with COVID-19

DG Alerts Findings from a study published in HeartRhythm showed that atrial fibrillation (AF) occurred in 17.6% of patients hospitalised with coronavirus disease 2019 (COVID-19) and that AF, particularly new-onset AF, was an independent predictor of in-hospital mortality. The study, conducted at 13 hospitals in the Northwell Health system, included 9,564 patients admitted between March 1 and […]

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Uncategorized Published - 5 February, 2021    By - Dr Clemens
Cancellation of Elective Surgery and Intensive Care Unit Capacity in New York State

AUTHORS: Poeran, Jashvant MD, PhD et al  Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1337-1341 BACKGROUND:  In response to the coronavirus disease 2019 (COVID-19) pandemic, New York State ordered the suspension of all elective surgeries to increase intensive care unit (ICU) bed capacity. Yet the potential impact of suspending elective […]

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Uncategorized Published - 5 February, 2021    By - Dr Clemens
Intensive Care Unit Capacity, Cancellation of Elective Surgery, and the US Pandemic Response

AUTHORS: Nurok, Michael MBChB, PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1334-1336 Until recently, conventional wisdom held that the United States had more intensive care unit (ICU) beds than it really needed. With higher supply of ICU beds per capita than other high-income countries, it appeared […]

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