Author: Dr Clemens

Uncategorized Published - 10 February, 2021    By - Dr Clemens
Comparison of Pupillometry With Surgical Pleth Index Monitoring on Perioperative Opioid Consumption and Nociception During Propofol–Remifentanil Anesthesia

AUTHORS: Kim, Jong Hae MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1589-1598 BACKGROUND:  Intraoperative monitoring with pupillometry has shown promising results for nociception/antinociception balance monitoring. However, its benefits in clinical practice remain unproven. The aim of this study was to evaluate the efficacy of intraoperative pupillometry […]

Read More
Uncategorized Published - 10 February, 2021    By - Dr Clemens
Safety of the LMA®Gastro™ for Endoscopic Retrograde Cholangiopancreatography

AUTHORS: Hagan, Katherine B. MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1566-1572 BACKGROUND:  Endoscopic retrograde cholangiopancreatography (ERCP) patients typically receive either tubeless anesthesia or general endotracheal anesthesia (GETA). Patients receiving propofol-based total intravenous anesthesia (TIVA) are at higher risk of sedation-related adverse events (SRAEs) than patients […]

Read More
Uncategorized Published - 10 February, 2021    By - Dr Clemens
Analysis of 1478 Cases of Hypospadias Repair: The Incidence of Requiring Repeated Anesthetic Exposure as Well as Exploration of the Involvement of Trainees on Case Duration

AUTHORS: Adler, Adam C. MS, MD, FAAP, FASE et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1551-1556 BACKGROUND:  Recently, there has been significant focus on the effects of anesthesia on the developing brain. Concern is heightened in children <3 years of age requiring lengthy and/or multiple anesthetics. Hypospadias […]

Read More
Uncategorized Published - 10 February, 2021    By - Dr Clemens
Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a “Vulnerable Brain”

AUTHORS: Shao, Yu Raymond MD, PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1529-1539 BACKGROUND:  A number of recent studies have reported an association between intraoperative burst suppression and postoperative delirium. These studies suggest that anesthesia-induced burst suppression may be an indicator of underlying brain vulnerability. A prominent […]

Read More
Uncategorized Published - 9 February, 2021    By - Dr Clemens
Preoperative Frailty Predicts Postoperative Neurocognitive Disorders After Total Hip Joint Replacement Surgery

AUTHORS: Evered, Lis A. PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1582-1588 BACKGROUND:  Frailty is a reduced capacity to recover from a physiologically stressful event. It is well established that preoperative frailty is associated with poor postoperative outcomes, but it is unclear if this includes cognitive […]

Read More
Uncategorized Published - 9 February, 2021    By - Dr Clemens
Arterial Catheters for Early Detection and Treatment of Hypotension During Major Noncardiac Surgery

AUTHORS: Naylor, Amanda J. MA et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1540-1550 BACKGROUND:  Continuous blood pressure monitoring may facilitate early detection and prompt treatment of hypotension. We tested the hypothesis that area under the curve (AUC) mean arterial pressure (MAP) <65 mm Hg is reduced by continuous […]

Read More
Uncategorized Published - 9 February, 2021    By - Dr Clemens
Real-Time Intraoperative Determination and Reporting of Cerebral Autoregulation State Using Near-Infrared Spectroscopy

AUTHORS: Montgomery, Dean PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1520-1528 BACKGROUND:  Cerebral blood flow (CBF) is maintained over a range of blood pressures through cerebral autoregulation (CA). Blood pressure outside the range of CA, or impaired autoregulation, is associated with adverse patient outcomes. Regional oxygen […]

Read More
Uncategorized Published - 9 February, 2021    By - Dr Clemens
Utilization Patterns of Perioperative Neuromuscular Blockade Reversal in the United States

AUTHORS: Dubovoy, Timur Z. MD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1510-1519 BACKGROUND:  Following the introduction of sugammadex to the US clinical practice, scarce data are available to understand its utilization patterns. This study aimed to characterize patient, procedure, and provider factors associated with sugammadex administration […]

Read More
Uncategorized Published - 9 February, 2021    By - Dr Clemens
Subset of COVID-19 patients have increased bleeding risk

DG Alerts Patients with coronavirus disease 19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions; however, in a subset of patients, there is also a risk of bleeding complications, according to a study published in Scientific Reports. “While the prothrombotic risk associated with COVID-19 is well recognised, the risk of bleeding should not […]

Read More
Uncategorized Published - 8 February, 2021    By - Dr Clemens
Exposure to General Anesthesia for Cesarean Delivery and Odds of Severe Postpartum Depression Requiring Hospitalization

AUTHORS: Guglielminotti, Jean MD, PhD et al Anesthesia & Analgesia: November 2020 – Volume 131 – Issue 5 – p 1421-1429 BACKGROUND:  Previous research suggests that, compared with regional anesthesia, general anesthesia is associated with increased odds of postoperative depressive disorders. No study has specifically evaluated the possible protective effect of neuraxial anesthesia for cesarean […]

Read More