Author: Dr Clemens

Uncategorized Published - 2 April, 2021    By - Dr Clemens
Machine Learning Applied to Registry Data: Development of a Patient-Specific Prediction Model for Blood Transfusion Requirements During Craniofacial Surgery Using the Pediatric Craniofacial Perioperative Registry Dataset

AUTHORS: Jalali, Ali PhD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 160-171 Background:  Craniosynostosis is the premature fusion of ≥1 cranial sutures and often requires surgical intervention. Surgery may involve extensive osteotomies, which can lead to substantial blood loss. Currently, there are no consensus recommendations for guiding blood […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Incidence of Anaphylaxis to Sugammadex in a Single-Center Cohort of 19,821 Patients

AUTHORS: Burbridge, Mark A. MD Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 93-97 Background:  Sugammadex is a modified cyclodextrin that is being increasingly used in anesthetic practice worldwide for the reversal of the aminosteroid neuromuscular blockers rocuronium and vecuronium. Its safety profile, however, is incompletely understood. One such aspect […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Intravenous Amisulpride Does Not Meaningfully Prolong the QTc Interval at Doses Effective for the Management of Postoperative Nausea and Vomiting

AUTHORS: Fox, Gabriel M. MB BChir et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 150-159 Background:  Postoperative nausea and vomiting (PONV) are significant issues in surgical patients, and additional treatment options are needed. Dopaminergic antiemetics have been popular for their efficacy, but their use has been limited by […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Nonselective Compared With Selective α-Blockade Is Associated With Less Intraoperative Hypertension in Patients With Pheochromocytomas and Paragangliomas

AUTHORS: Kong, Hao MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 140-149 Background:  Both selective and nonselective α-blockade are used for preoperative preparation in patients with pheochromocytomas and paragangliomas (PPGLs). However, the effects of different types of α-blockade on perioperative outcomes remain inconclusive. This study was designed […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Intraoperative Cardiac Arrest During Adult Liver Transplantation: Incidence and Risk Factor Analysis From 7 Academic Centers in the United States

AUTHORS: Smith, Natalie K MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 130-139 Background:  Intraoperative cardiac arrest (ICA) has a reported frequency of 1 in 10,000 anesthetics but has a much higher estimated incidence in orthotopic liver transplantation (OLT). Single-center studies of ICA in OLT are limited […]

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Uncategorized Published - 1 April, 2021    By - Dr Clemens
Retrograde Autologous Priming in Cardiac Surgery

AUTHORS: Hensley, Nadia B. MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 100-107 Background:  Retrograde autologous priming (RAP) before cardiopulmonary bypass (CPB) may minimize allogeneic red cell transfusion. We conducted a systematic review of the literature to examine the impact of RAP on perioperative allogeneic red cell […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
The Attributable Mortality of Postoperative Bleeding Exceeds the Attributable Mortality of Postoperative Venous Thromboembolism

AUTHORS: Bellomy, Melissa L. MD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 82-88 Background:  Bleeding and venous thromboembolic disease are considered important sources of postoperative morbidity and mortality. Clinically, treatment of these 2 disorders is often competing. We sought to better understand the relative contributions of bleeding […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
Effectiveness of Prone Positioning in Nonintubated Intensive Care Unit Patients With Moderate to Severe Acute Respiratory Distress Syndrome by Coronavirus Disease 2019

AUTHORS: Taboada, Manuel MD, PhD et al Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 25-30 Background:  In the treatment for severe acute respiratory distress syndrome (ARDS) from coronavirus disease 2019 (COVID-19), the World Health Organization (WHO) recommends prone positioning (PP) during mechanical ventilation for periods of 12–16 h/d to […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
Neuromuscular and Clinical Recovery in Thoracic Surgical Patients Reversed With Neostigmine or Sugammadex

AUTHORS: Murphy, Glenn S. MD et al Anesthesia & Analgesia: December 10, 2020 – Volume – Issue – 10 BACKGROUND: Patients undergoing thoracoscopic procedures may be at high-risk for incomplete neuromuscular recovery and associated complications. The aim of this clinical investigation was to assess the incidence of postoperative residual neuromuscular blockade in adult thoracic surgical […]

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Uncategorized Published - 31 March, 2021    By - Dr Clemens
A Bayesian Comparison of Frailty Instruments in Noncardiac Surgery

AUTHORS: McIsaac, Daniel I. MD, MPH, FRCPC et al Anesthesia & Analgesia: November 30, 2020 – Volume – Issue – 10 BACKGROUND: Frailty—a multidimensional syndrome related to age- and disease-related deficits—is a key risk factor for older surgical patients. However, it is unknown which frailty instrument most accurately predicts postoperative outcomes. Our objectives were to […]

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